|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Epidemiological studies have already consistently demonstrated significant elevated circulating Fet-A in the course of obesity and related complications, such as type 2 diabetes mellitus, metabolic syndrome, and nonalcoholic fatty liver disorder (NAFLD).
|
31766373 |
2019 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Effects of exercise training on Fetuin-a in obese, type 2 diabetes and cardiovascular disease in adults and elderly: a systematic review and Meta-analysis.
|
30670052 |
2019 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
As a multifunctional protein, fetuin-A has positive effects on health such as calcification, cardiovascular diseases and tumor development processes with various mechanisms, whereas it plays a negative role in the processes of obesity, diabetes and fatty liver disease.
|
31232084 |
2019 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Together, our studies demonstrate that phosphorylation status of Fet-A (Ser312) is associated with obesity and insulin resistance and raise the possibility that Fet-A phosphorylation may play a role in regulation of insulin action.
|
31084489 |
2019 |
|
Obesity
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Fetuin-A levels increased in association with diabetes in SAT but not in circulation in the obese subjects.
|
30579336 |
2018 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Fetuin-A has been linked to insulin resistance and obesity.
|
29127490 |
2018 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Higher serum fetuin-A levels in obese T2DM patients compared with non-obese patients and obese NGT subjects supports the hypothesis that fetuin-A may be as a bridge connecting obesity and obesity-related T2DM.
|
29174342 |
2018 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Multiple logistic regression analysis revealed that both individuals without obesity (<i>P</i> for trend = 0.017) and with obesity (<i>P</i> for trend = 0.028) in the higher tertiles of fetuin-A had an increased risk of MA than those in the lowest tertile.
|
30675162 |
2018 |
|
Obesity
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The overall aims of this study were: (1) to investigate the associations of fetuin-A with adiposity and insulin resistance, as well as its relationship with adipokines, in prepubertal children, and, (2) to evaluate whether, in prepubertal obesity, serum fetuin-A levels may either change or predict the responsiveness to an educational-based weight excess reduction program.
|
27388590 |
2017 |
|
Obesity
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
These results indicate FetA's involvement in the lowering of adiponectin level in obesity induced diabetic mice.
|
27720679 |
2017 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Human Fetuin-A Rs4918 Polymorphism and its Association with Obesity in Healthy Persons and in Patients with Myocardial Infarction in Two Hungarian Cohorts.
|
27487851 |
2016 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of human fetuin-A rs4917 polymorphism with obesity in 2 cohorts.
|
25695715 |
2015 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Fetuin-A was recently identified as a novel hepatokine which is associated with obesity, insulin resistance and non-alcoholic fatty liver disease.
|
23948064 |
2013 |
|
Obesity
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
As we observed an association between higher fat mass and elevated AHSG levels, these preliminary results may form the basis of further study to establish if the observed associations may be one reason why obesity has been reported to constitute a survival advantage in CKD.
|
18337634 |
2008 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We genotyped 356 overweight or obese (BMI: 37.2 [25.0-66.5] kg/m(2)) and 148 lean (BMI: 23.7 [23.4-24.9] kg/m(2)) otherwise healthy Swedish men for three non-synonymous single-nucleotide polymorphisms (SNPs) within exon 6 (rs4917) and exon 7 (rs4918 and Arg299Cys) and one SNP in intron 1 (rs2593813) of the AHSG gene.
|
15806395 |
2005 |