AIF1, allograft inflammatory factor 1, 199

N. diseases: 166; N. variants: 8
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.220 AlteredExpression phenotype BEFREE Oxyntomodulin was observed to attenuate TNF‑α‑induced pain hypersensitivity in mice, as well as the expression of IBA1, NF‑κB p‑p65, IL‑6 and IL‑1β in the spinal cord. 31661136 2019
CUI: C0030193
Disease: Pain
Pain 		0.220 AlteredExpression phenotype BEFREE Puerarin or ERK inhibitor PD98059 alleviated pain behaviors, decreased expression of microglia marker ionized calcium-binding adaptor molecule 1 (Iba-1) in rats with NP implantation. 30466510 2018
CUI: C0030193
Disease: Pain
Pain 		0.220 Biomarker phenotype RGD Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling. 18186080 2008