ELANE, elastase, neutrophil expressed, 1991

N. diseases: 346; N. variants: 33
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
0.200 Biomarker disease RGD The present study was designed to elucidate the role of nitric oxide (NO), inducible NO synthase (iNOS), neutrophil elastase (NE) and other mediators in the ALI caused by PMA. 18283562 2008
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
0.200 Therapeutic disease RGD This study investigated whether sivelestat, a specific NE inhibitor, can attenuate ALI induced by HSR in rats. 17203197 2007
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
0.200 Therapeutic disease RGD Beneficial effect of an inhibitor of leukocyte elastase (EPI-hNE-4) in presence of repeated lung injuries. 15257085 2004