ELANE, elastase, neutrophil expressed, 1991

N. diseases: 346; N. variants: 33
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.130 Biomarker disease BEFREE These results suggest that miR-608 is an important posttranscriptional regulator of ELANE expression in human monocytes and may play an important role in the process of inflammation. miR-608 and neutrophil elastase may be novel targets for the diagnosis or treatment of sepsis. 31749032 2020
CUI: C0243026
Disease: Sepsis
Sepsis 		0.130 Biomarker disease BEFREE However, the contribution of neutrophil elastase (NE) to myocardial injury in sepsis is still unknown. 31764619 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.130 Biomarker disease BEFREE Also, whereas NE-deficient mice had impaired survival in response to E. coli sepsis, as compared to wild-type mice, the presence or absence of NE had no influence on survival in response to sepsis that had been induced with OmpA-deficient E. coli. 10947984 2000
CUI: C0243026
Disease: Sepsis
Sepsis 		0.130 Biomarker disease HPO