Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.020 GeneticVariation disease BEFREE A retrospective review of all surgical cases included in the DANTE trial from 2001 to 2006 for lung cancer screening was performed. 30875336 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.020 GeneticVariation disease BEFREE A retrospective review of all surgical cases included in the DANTE trial from 2001 to 2006 for lung cancer screening was performed. 30875336 2019
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.020 GeneticVariation disease BEFREE A retrospective review of all surgical cases included in the DANTE trial from 2001 to 2006 for lung cancer screening was performed. 30875336 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.020 GeneticVariation disease BEFREE A human iPSC line was generated from exfoliated renal epithelial (ERE) cells of a patient affected with Congenital Heart Disease (CHD) and Laterality Defects carrying tshe variant p.R152H in the DAND5 gene. 29136563 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.020 Biomarker disease BEFREE Altogether, our results provide new insight into the molecular mechanism of the laterality defects and related CHDs, priming for the first time DAND5 as one of multiple candidate determinants for CHDs in humans. 28738792 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 AlteredExpression group BEFREE High serum DAND5 levels were significantly correlated with tumor differentiation, large tumor size, advanced Tumor Node Metastasis (TNM) stage, lymph node and liver metastasis, high carcinoembryonic antigen level, recurrence, poor overall and disease-free survival. 28815037 2017
CUI: C0152021
Disease: Congenital heart disease
Congenital heart disease
0.020 GeneticVariation group BEFREE A human iPSC line was generated from exfoliated renal epithelial (ERE) cells of a patient affected with Congenital Heart Disease (CHD) and Laterality Defects carrying tshe variant p.R152H in the DAND5 gene. 29136563 2017
CUI: C0152021
Disease: Congenital heart disease
Congenital heart disease
0.020 GeneticVariation group BEFREE Functional study of DAND5 variant in patients with Congenital Heart Disease and laterality defects. 28738792 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 AlteredExpression group BEFREE Cultured NSCLC cells expressed higher levels of SP-1 protein than normal airway epithelial cells, and double-fluorescence immunohistochemistry showed a strong correlation between SP-1 and VEGF in human NSCLC tumors. 22992725 2012
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.020 GeneticVariation disease BEFREE The size of CER2 is about 1 Mb, according to the Homo Sapiens Complete Genome databases at EMBL, and is located about 0.5 Mb centromeric to the known homozygous deletion region, identified in lung cancer. 12007195 2002
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.020 GeneticVariation disease BEFREE The size of CER2 is about 1 Mb, according to the Homo Sapiens Complete Genome databases at EMBL, and is located about 0.5 Mb centromeric to the known homozygous deletion region, identified in lung cancer. 12007195 2002
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung
0.020 GeneticVariation disease BEFREE The size of CER2 is about 1 Mb, according to the Homo Sapiens Complete Genome databases at EMBL, and is located about 0.5 Mb centromeric to the known homozygous deletion region, identified in lung cancer. 12007195 2002
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.010 Biomarker disease BEFREE Compared with CE-MRV, DANTE-SPACE showed no significant difference in the ability to detect deep venous thrombosis of the lower extremities. 31446527 2019
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.010 Biomarker group BEFREE This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease. 29730570 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 AlteredExpression disease BEFREE A significant positive correlation existed between serum DAND5 levels and matched DAND5 expression in CRC tissues. 28815037 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 Biomarker phenotype BEFREE Elevated serum DAND5 is associated with metastasis and predicts poor prognosis in colorectal cancer. 28815037 2017
Secondary malignant neoplasm of liver
0.010 AlteredExpression disease BEFREE High serum DAND5 levels were significantly correlated with tumor differentiation, large tumor size, advanced Tumor Node Metastasis (TNM) stage, lymph node and liver metastasis, high carcinoembryonic antigen level, recurrence, poor overall and disease-free survival. 28815037 2017
Malignant neoplasm of colon and/or rectum
0.010 Biomarker disease BEFREE Elevated serum DAND5 is associated with metastasis and predicts poor prognosis in colorectal cancer. 28815037 2017
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 AlteredExpression disease BEFREE Cultured NSCLC cells expressed higher levels of SP-1 protein than normal airway epithelial cells, and double-fluorescence immunohistochemistry showed a strong correlation between SP-1 and VEGF in human NSCLC tumors. 22992725 2012