Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE A recent study showed that increased plasma levels of the NET biomarker, citrullinated histone H3 (H3Cit), are associated with venous thromboembolism in pancreatic and lung cancer but not in other types of cancer, including breast cancer. 31048354 2020
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE NET-U represents an aggressive form of uterine malignancy. 31074241 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE In MDA-MB-231 breast cancer cells, knockdown of RSK2 or ELK3 suppressed cell proliferation with accumulation at the G1 cell cycle phase, resulting in inhibition of foci formation and anchorage-independent cancer colony growth in soft agar. 31018569 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 GeneticVariation group BEFREE We present a case of a 58-year-old adult patient with dyspeptic symptoms who was incidentally diagnosed with triple malignancy (pheochromocytoma, multiple GISTs of small intestine and an ampullary NET) as a first manifestation of NF1. 31301733 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE Family history of any cancer, family history of colorectal cancer and history of ever smoking were associated with an increased risk of SI-NET by meta-analysis. 28394712 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE In addition, we identified the molecular mechanism by which ELK3 promotes cancer cell migration and invasion. 27959451 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 AlteredExpression group BEFREE Bioinformatic analysis of cancer RNA-seq data shows that hsa-miR-155-5p and ELK3 expression are significantly anti-correlated, as would be expected from hsa-miR-155-5p targeting ELK3 RNA. 25401928 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE Cases in which the primary cannot be located are referred to as NET with CUP-syndrome (cancer of unknown primary syndrome). 21681495 2011
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.090 Biomarker group BEFREE Nevertheless, K-ras mutation screening may increase the sensitivity of FNA and ERP cytology and may be useful in identifying pancreatitis patients at high risk for developing cancer, and as a adjunct with cytology to differentiate pancreatic cancer from chronic pancreatitis. 14966900 2004