Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Squamous cell carcinoma of esophagus
0.350 AlteredExpression disease BEFREE In conclusion, findings of this study showed that ZNF750, EP300, MTOR and KMT2D heterogeneously expressed in ESCC. 30528923 2019
Squamous cell carcinoma of esophagus
0.350 AlteredExpression disease BEFREE Immunohistochemical analysis showed that EP300 expression was significantly higher in ESCC tumor tissues, and the expression levels were associated with poor survival of ESCC patients. 31632486 2019
Squamous cell carcinoma of esophagus
0.350 Biomarker disease BEFREE EP300 which has previously been implicated in the genesis of ESCC had a missense variant segregating in three affected individuals in a single family. 28165652 2017
Squamous cell carcinoma of esophagus
0.350 Biomarker disease CTD_human Genetic landscape of esophageal squamous cell carcinoma. 25151357 2014
Squamous cell carcinoma of esophagus
0.350 Biomarker disease BEFREE Moreover, we have found that several important histone regulator genes (MLL2 (also called KMT2D), ASH1L, MLL3 (KMT2C), SETD1B, CREBBP and EP300) are frequently altered in ESCC. 24670651 2014
Squamous cell carcinoma of esophagus
0.350 Biomarker disease CTD_human In OSCC samples, 65% of those with deep tumour invasion (adventitia) and 63% samples with metastasis revealed p300 promoter methylation (p<0.05). p300 mRNA expression was observed in 19.0% (4/21) of methylated tumours and 58.6% (17/29) of unmethylated tumours (p = 0.005). 17965222 2007
Squamous cell carcinoma of esophagus
0.350 AlteredExpression disease BEFREE In OSCC samples, 65% of those with deep tumour invasion (adventitia) and 63% samples with metastasis revealed p300 promoter methylation (p<0.05). p300 mRNA expression was observed in 19.0% (4/21) of methylated tumours and 58.6% (17/29) of unmethylated tumours (p = 0.005). 17965222 2007