EPAS1, endothelial PAS domain protein 1, 2034

N. diseases: 293; N. variants: 35
Disease: Anoxia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 AlteredExpression phenotype LHGDN Heterogeneity in binding and gene-expression regulation by HIF-2alpha. 18423372 2008
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 AlteredExpression phenotype LHGDN Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2. 18055454 2008
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 Biomarker phenotype LHGDN Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and -independent pathways. 18077449 2008
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 Biomarker phenotype LHGDN Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia. 16263938 2006
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 Biomarker phenotype LHGDN The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer. 16278385 2005
CUI: C0003130
Disease: Anoxia
Anoxia 		0.060 Biomarker phenotype LHGDN Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. 14744852 2004