EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease LHGDN These results suggest that rs1617640 in the EPO promoter is significantly associated with PDR and ESRD. 18458324 2008
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE In the light of the enthusiasm regarding the use of recombinant human erythropoietin (Epo) and its analogues for treatment of the anaemias of chronic renal failure and malignancies it is worth remembering that today's success has been based on a century of laborious research. 17253966 2007
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Therapeutic disease CTD_human Efficacy of darbepoetin in doxorubicin-induced cardiorenal injury in rats. 16707910 2006
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Human erythropoietin gene therapy for patients with chronic renal failure. 15798000 2005
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE In conclusion, the erythropoiesis in chronic renal failure could be attributed to the influence of QA on EPO synthesis. 12620922 2003
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 GeneticVariation disease BEFREE Purified 1 x 10(4) circulating CD34+ cells isolated from rHuEPO-hyporesponsive HD patients (EPO-H; n = 10), rHuEPO-responsive non-HD patients with CRF (EPO-R; n = 8), nonanemic HD patients without rHuEPO therapy (EPO-W/O; n = 10), and healthy volunteer controls (CON; n = 10) were subjected to a methylcellulose culture system supplemented with rHuEPO, recombinant human interleukin-3 (IL-3), recombinant human stem cell factor (SCF), and recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) for 14 days. 12612986 2003
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE We evaluated the efficacy of EPO gene therapy using adenovirus vector for chronic renal failure mice expressing severe renal anemia. 10200985 1999
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE The transplantation of polymer encapsulated myoblasts genetically engineered to secrete erythropoietin (Epo) may obviate the need for repeated parenteral administration of recombinant Epo as a treatment for chronic renal failure, cancer or AIDS-associated anemia. 10326023 1998
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Short-term effect of erythropoietin on T-cell mitogenic proliferation in chronic renal failure patients. 8903857 1996
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Anemia is an invariable consequence of end-stage renal failure (ESRF) and recombinant erythropoietin has dramatically improved the quality of life of patients with ESRF. 7706487 1995
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE The peripheral red cell count is kept constant by a closely controlled feedback mechanism involving O2 supply, erythropoietin secretion and erythropoiesis; the system may become unbalanced in conditions such as chronic renal disease, chronic inflammation and prematurity. 7658325 1995
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Recombinant human erythropoietin represents a major breakthrough in the treatment of patients with chronic renal failure. 1992884 1991