EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE In a cohort of patients diagnosed with acute kidney injury after cardiopulmonary bypass surgery, the decreased TG and cholesterol negatively correlated with increased EPO in serum. 31740386 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Erythropoietin modulates macrophages but not post-ischemic acute kidney injury in mice. 30414800 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Endogenous Erythropoietin and Hepatic Dysfunction in Acute Kidney Injury Requiring Renal Replacement Therapy. 30712038 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial. 30132785 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Data showed that EPO attenuates renal microvascular damage during septic-AKI progression through a) the decrease of HIF-1 alpha, iNOS, and NF-κB and b) the enhancement of EPO-R, PeCAM-1, VEGF, and VEGFR-2 expression. 30257316 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 AlteredExpression disease BEFREE Here we tested whether an acute increase of plasma erythropoietin induces FGF23 expression in erythropoietic cells of bone marrow thereby contributing to the increase of circulating FGF23 in AKI. 29395333 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Compared with placebo, the odds ratio (OR) for the occurrence of AKI was 0.24 [95% confidence interval (CI) 0.16-0.34] with natriuretic peptide, 0.33 (95% CI 0.14-0.70) with fenoldopam, 0.54 (95% CI 0.31-0.84) with dexmedetomidine, 0.56 (95% CI 0.29-0.95) with low-dose erythropoietin, 0.63 (95% CI 0.43-0.88) with levosimendan, 0.76 (95% CI 0.52-1.10) with steroids, 0.83 (95% CI 0.48-1.40) with high-dose erythropoietin, 0.85 (95% CI 0.64-1.14) with N-acetylcysteine, 0.96 (95% CI 0.69-1.29) with sodium bicarbonate, and 1.05 (95% CI 0.70-1.41) with statins. 28819767 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 AlteredExpression disease BEFREE Critically ill patients (AKI and non-AKI groups) had higher serum levels of Epo than healthy volunteers. 23566289 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Therefore, in the present study, we determined whether EPO could exert an impact on the dynamics of macrophages in a well-established model of rhabdomyolysis-induced acute kidney injury and explored the potential mechanisms. 28383559 2017
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Biomarker disease BEFREE Based on the results here, we conclude that HEPC, EPO and HIF-1α are involved in the pathogenesis of sepsis-induced AKI and confirm the dominating effects of inflammatory determinants over hypoxia-related complications. 27266727 2016
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Therapeutic disease CTD_human This study suggests that EPO exerts renoprotection on an experimental model of LPS-induced AKI. 24561306 2014
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.400 Therapeutic disease CTD_human Mouse Epo-secreting MSCs were generated, tested in vitro, and then implanted by intraperitoneal injection in allogeneic mice previously administered cisplatin to induce AKI. 21847101 2011