EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE We investigated early changes in and effects of EPO on renal tissues of rats with myocardial infarction by morphology and immunohistochemistry. 29671622 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 AlteredExpression disease BEFREE As CO also increases serum EPO levels in human volunteers, these findings continue to support therapeutic use of CO to treat IRI in association with organ transplantation, stroke, and myocardial infarction. 29463714 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE We studied 60 Wistar rats divided into the following groups: control (CT), control + EPO (CT + EPO), myocardial infarction + EPO (MI + EPO), and myocardial infarction (MI). 29120671 2018
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE We assessed the effects of combined polyethylene glycol hydrogel (PEG), human induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM), and erythropoietin (EPO) therapy in a rat model of myocardial infarction. 28988988 2017
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE Despite the promising preclinical data, large cohort clinical studies in humans failed to show a significant amelioration in cardiac function upon systemic injection of EPO in patients with myocardial infarctions. 28629520 2017
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE Combined VEGF gene transfer and erythropoietin in ovine reperfused myocardial infarction. 21944383 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE Erythropoietin administration after myocardial infarction reduced the area of infarction and hemorrhage. 23453036 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE Migration of bone marrow-derived cells and improved perfusion after treatment with erythropoietin in a murine model of myocardial infarction. 21362129 2012
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE The purpose of this study is to investigate the protective effects of EPO in porcine MI. 22038108 2012
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease BEFREE EPO-alfa (10 IU/mL) was used in vitro and darbepoetin alfa (40 microg/kg/3 weeks, starting 3 weeks after MI) in vivo. 20139114 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 Biomarker disease CTD_human The association of intense isometric exercise, abuse of erythropoietin and nandrolone is likely to have predisposed to coronary thrombus formation and acute myocardial infarction, as the patient presented no traditional cardiovascular risk factors. 19337937 2009
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.400 AlteredExpression disease BEFREE This study demonstrates for the first time that, despite high hematocrit levels, endogenously overexpressed EPO provides protection against myocardial infarction in a murine model of permanent LAD ligation. 17998053 2007