ERBB3, erb-b2 receptor tyrosine kinase 3, 2065

N. diseases: 318; N. variants: 16
Disease: Head and Neck Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 AlteredExpression disease BEFREE MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer. 30694565 2019
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 Biomarker disease BEFREE Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer. 29440171 2018
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 Biomarker disease BEFREE Human Papillomavirus Regulates HER3 Expression in Head and Neck Cancer: Implications for Targeted HER3 Therapy in HPV<sup>+</sup> Patients. 27986750 2017
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 AlteredExpression disease BEFREE Although heregulin and human epidermal growth factor receptor 3 (HER3) are frequently expressed at high levels in patients with head and neck cancer, their prognostic value remains unclear. 26195293 2015
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 Biomarker disease BEFREE Human epidermal growth factor receptor 3 (HER3) blockade with U3-1287/AMG888 enhances the efficacy of radiation therapy in lung and head and neck carcinoma. 23998444 2013
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 AlteredExpression disease BEFREE erbB-3, a third member of the erbB/epidermal growth factor receptor gene family: its expression in head and neck cancer cell lines. 8286103 1993
CUI: C3887461
Disease: Head and Neck Carcinoma
Head and Neck Carcinoma 		0.360 CausalMutation disease CGI