DisGeNET - a database of gene-disease associations

ERBB4, erb-b2 receptor tyrosine kinase 4, 2066

N. diseases: 317; N. variants: 75

Disease: AMYOTROPHIC LATERAL SCLEROSIS 19 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C3715155
Disease:	AMYOTROPHIC LATERAL SCLEROSIS 19

AMYOTROPHIC LATERAL SCLEROSIS 19

0.700

GeneticVariation

disease

UNIPROT

ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 19.

24119685

2013

CUI:	C3715155
Disease:	AMYOTROPHIC LATERAL SCLEROSIS 19

AMYOTROPHIC LATERAL SCLEROSIS 19

0.700

Biomarker

disease

GENOMICS_ENGLAND

ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 19.

24119685

2013

CUI:	C3715155
Disease:	AMYOTROPHIC LATERAL SCLEROSIS 19

AMYOTROPHIC LATERAL SCLEROSIS 19

0.700

CausalMutation

disease

CLINVAR

CUI:	C3715155
Disease:	AMYOTROPHIC LATERAL SCLEROSIS 19

AMYOTROPHIC LATERAL SCLEROSIS 19

0.700

Biomarker

disease

GENOMICS_ENGLAND

CUI:	C3715155
Disease:	AMYOTROPHIC LATERAL SCLEROSIS 19

AMYOTROPHIC LATERAL SCLEROSIS 19

0.700

Biomarker

disease

CTD_human