AKT1, AKT serine/threonine kinase 1, 207

N. diseases: 1250; N. variants: 33
Disease: Cutaneous Melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 Biomarker disease BEFREE Subsequently, MCM7 expression vector and lentivirus RNA used for MCM7 silencing (LV-shRNA-MCM7) were constructed, and these vectors, dimethyl sulfoxide (DMSO) and AKT activator SC79 were then introduced into CM cell line SK-MEL-2 to validate the role of MCM7 in cell autophagy, viability, apoptosis, cell cycle, migration, and invasion. 31535400 2020
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 Biomarker disease BEFREE Immune checkpoint and serine/threonine-protein kinase inhibitors have become a standard of care for advanced cutaneous melanoma, but dacarbazine-based chemotherapies are occasionally used. 30396963 2018
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 CausalMutation disease CGI