Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.430 GeneticVariation disease BEFREE However, the combined variant genotypes of the four loci with P(trend) approaching to 0.10 (rs2228526, rs4253160, rs12571445 and rs3793784) were associated with a significantly increased lung cancer risk (adjusted OR 1.35, 95% CI, 1.04-1.75 among subjects carrying three or more variant alleles), indicating that multiple loci in ERCC6 may jointly contribute to the susceptibility of lung cancer. 18789574 2009
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.430 GeneticVariation disease BEFREE Our data constituted strong evidence that ERCC6 rs3793784:C>G alters its transcriptional activity and may confer personalized susceptibility to lung cancer. 17854076 2008
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.430 Biomarker disease BEFREE Our results suggest that individuals whose expression levels of XPG/ERCC5 and CSB/ERCC6 are reduced may be at higher risk of lung cancer. 10910954 2000
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.430 Biomarker disease GENOMICS_ENGLAND
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.430 CausalMutation disease CLINVAR