|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
High-performance albumin dialysis improves survival and key clinical and laboratory parameters in severe ACLF and AKI.
|
31267563 |
2020 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
In an open-label, randomized controlled trial (RCT), consecutive patients with ACLF diagnosed with HRS acute kidney injury (AKI) were randomized to albumin with infusion of terlipressin (2-12 mg/day; n = 60) or noradrenaline (0.5-3.0 mg/h; n = 60).
|
30076614 |
2020 |
|
Kidney Failure, Acute
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Poor cardiac function (left ventricular ejection fraction < 35%) prior to surgery was a significant contributing factor associated with the onset of AKI [odds ratio (OR) 5.55, 95% confidential interval (CI) 1.39-22.13; P = 0.015], while a longer duration from diagnosis to surgical repair (OR 0.97, 95% CI 0.95-1.00; P = 0.049) and a higher preoperative albumin level (OR 0.83, 95% CI 0.70-0.99; P = 0.041) were found to lower the risk of AKI.
|
31005966 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The patients with AKI had significantly higher mean value of CRP and CAR (0.29 [0.16-0.50] vs. 0.55 [0.37-1.05]; p<0.001) and lower mean levels of albumin than those without AKI.
|
30293924 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Male sex, older age, underlying diabetes and hypertension, lower serum albumin and plasma hemoglobin, more frequent radio-contrast exposure, entrance of clinical trials, and receiving chemotherapy were associated with AKI occurrence.
|
30968593 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Today, once-forbidden albumin is the recommended colloid in severe sepsis and septic shock, and the European Medical Agency is considering the removal of starch solutions from the European market because of an increased incidence of acute kidney injury and mortality.
|
30715722 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
LDL and albumin did not have sufficient power to predict the 90 days in-hospital mortality of critically ill older patients with AKI.
|
31695346 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to determine changes in uremic toxins: creatinine, urea, uric acid, asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), trimethylamine N-oxide (TMAO) and urinary makers of AKI: albumin, neutrophil gelatinase-associated lipocalin (uNGAL), kidney injury molecule-1 and cystatin-C (uCyst-C) after long runs.
|
31661892 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Using double needles for ablation was a risk factor for nonoliguric AKI, while high preoperative levels of red blood cells (RBC), hemoglobin (HGB) and albumin (Alb) were risk factors for oliguric AKI.
|
30204038 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Evaluation of AKI was made with a diagnostic algorithm that included identification and removal/treatment of precipitating factors and albumin administration (1 g/kg for 2 days) to patients with AKI stage 1B or greater.
|
30810244 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Six other urine biomarkers urine albumin, urine beta2-microglobulin, urine kidney injury molecule-1, urine cystatin C, urine trefoil factor-3 and urine osteopontin either had minimal elevation, and/or minimal prediction for AKI stage 2/3 (AUC-ROC<0.7).
|
31260445 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Univariate analyses of the PE group identified low preoperative serum albumin levels, low antithrombin III (ATIII) activities, and urine protein/creatinine ratios (U-P/Cr) as significant predictors of AKI.
|
31269838 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
In CM, AKI was associated with the presence and severity of retinopathy (p < 0.05) and increased cerebrospinal fluid albumin suggestive of blood-brain barrier disruption.
|
31109328 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Low albumin level may be associated with poor prognosis of pediatric AKI.
|
31357204 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
After adjusting for age, sex, diabetes, hypertension, albumin, and MELD-Na score as covariates on multivariable logistic regression, uromodulin was independently associated with AKI [odd ratios of 1.19 (95% confidence interval 1.02, 1.37; <i>P</i> = 0.02)].
|
31411505 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our data indicate that albumin and trefoil factor-3 may have value in the early diagnosis of kidney injury in non-rodent species and may thus inspire the preclinical use of urinary biomarkers in drug-induced acute kidney injury.
|
30394304 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Progression to frequently relapsing nephrotic syndrome/steroid-dependent nephrotic syndrome in 3 years was seen in 44.2% of the patients and was shown by the Cox regression analysis to be significantly related to younger age and days until remission at the first episode, but not to sex, hematuria, the minimum serum albumin level or AKI.
|
31550360 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
The predictors of AKI at ICU admission included hypertension [odds ratio (OR) = 1.44, p 0.017], high serum creatinine concentration [OR = 3.54; p < 0.001], low serum albumin concentration [OR = 1.42, p 0.015], high APACHE II score [OR = 2.10; p < 0.001] and high SAPS 3 [OR = 1.75; p < 0.001].
|
31792326 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
AKI incidence was higher in patients with preoperative serum albumin < 37.5 g/L than in those with preoperative serum albumin ≥37.5 g/L [35.9% (98/273) vs. 19.7% (90/456), P < 0.001].
|
31477030 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Albumin may be beneficial in septic shock, but other colloids such as starches, dextrans, and gelatins appear to increase the risk of death and acute kidney injury.
|
29986619 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Mean arterial pressure (MAP), platelet count, and serum albumin were significantly lower and total leucocyte count (TLC), blood urea nitrogen, serum creatinine (SCr), total bilirubin, aspartate aminotransferase, international normalized ratio, Child-Turcotte-Pugh (CTP) score, and model for end-stage liver disease (MELD) score higher in cirrhosis patients with AKI than without AKI (p < 0.05 each).
|
31830752 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
The addition of urinary NGAL/albumin to the clinical model modestly improved the prediction of AKI, in particular severe stage 3 AKI (area under the curve [AUC] of 0.9 from 0.87, p = 0.369) and the prediction of 30-day RRT or death (AUC 0.83 from 0.79, p = 0.139).
|
31203271 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
Biomarker
|
disease |
BEFREE |
Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury.
|
31101366 |
2019 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The preoperative serum albumin level was associated with postoperative AKI (odds ratio [OR] 0.506, 95% confidence interval [CI] 0.325-0.788; P = 0.003).
|
29992550 |
2018 |
|
Kidney Failure, Acute
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Multivariable logistic regression analysis showed that male sex (OR, 4.45; 95% CI, 1.80-11.82; P = 0.002), preoperative use of beta-blockers (OR, 4.81; 95% CI, 1.24-16.50; P = 0.016), low preoperative serum albumin levels (OR, 0.29; 95% CI, 0.11-0.76; P = 0.011), and colloid administration (OR, 5.18; 95% CI, 1.42-18.15; P = 0.011) were associated with postoperative AKI.
|
30201973 |
2018 |