ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE This difference was more pronounced in patients who had glomerulonephritis (HR = 0.72) or hypertension (HR = 0.81) than in those with end-stage renal disease (ESRD) due to diabetes mellitus or other causes.<i>Conclusion:</i>Peritoneal dialysis is less likely to be the first dialysis modality in patients with low serum albumin requiring dialysis. 30852522 2020
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Recently, changes in urinary albumin and in GFR have been recognized as risk factors for the development of end-stage kidney disease and mortality. 31577820 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Patients are included in the registry based on the following criteria: 1) two estimated glomerular filtration rate (eGFR) results < 60 ml/min/1.73m<sup>2</sup> separated by 90 days, including the most recent eGFR being < 60 ml/min/1.73m<sup>2</sup>; or 2) the most recent two urine protein values > 300 mg protein/g creatinine on either urine total protein/creatinine ratio or urine albumin/creatinine ratio; or 3) an EHR problem list diagnosis of end stage renal disease (ESRD). 30823871 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Lower pre-ESRD serum albumin was associated with higher post-ESRD all-cause, cardiovascular, and infection-related mortalities and hospitalization rates. 30642656 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Serum albumin and hospitalization among pediatric patients with end-stage renal disease who started dialysis therapy. 31218394 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE The GNRI was calculated by incorporating serum albumin and anthropometric measurements in 326 patients with nondialysis stage 3-5 CKD who were followed up from September 2011 to March 2017 for end-stage renal disease (ESRD) and the composite outcome of all-cause death and cardiovascular events. 31739530 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Our study shows: (i) a survival free from ESKD in two-thirds of patients at 1 year and in one-half at 2 years and (ii) a significant reduction or even a discontinuation of albumin infusions allowing ambulatory care in a subset of patients. 29474669 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 AlteredExpression disease BEFREE We evaluated the effects of HIV infection on serum albumin levels in ESRD patients starting continuous ambulatory PD (CAPD) and mortality outcomes. 31181128 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 GeneticVariation disease BEFREE Risk of ESRD was associated with male sex; younger age; lower estimated glomerular filtration rate (eGFR); higher albumin/creatinine ratio, HbA<sub>1c</sub>, and systolic blood pressure; and smoking. 30455333 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE We further examined the association between AG and incident end-stage renal disease (ESRD) using frailty models, adjusting for demographics, clinical factors, body mass index, serum albumin, bicarbonate, eGFR, and urinary albumin-to-creatinine ratio by following 558 adults with moderate CKD for 12 yr via the United States Renal Data System. 30908932 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE However, both strategies are associated with increased albumin loss into the dialysate, raising concerns about the potential for decreased serum albumin concentrations that have been associated with poor outcomes in ESKD. 30102329 2019
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Normal or mildly increased 24-hour urinary albumin excretion (<30mg/d) at baseline was present in 28% of participants, but in only 5% of those progressing to ESKD. 29784612 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE p-Cresyl glucuronide (p-CG) is a by-product of tyrosine metabolism that accumulates in patients with end-stage renal disease. p-CG binding to human serum albumin in physiological conditions (37 °C, pH 7.40) was studied by ultrafiltration (MWCO 10 kDa) and data were analyzed assuming one binding site. 29705133 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 AlteredExpression disease BEFREE The primary predictive factors were the 4-variable (age, sex, bedside Schwartz estimated glomerular filtration rate, and ratio of albumin to creatinine levels) and 8-variable (4 variables plus serum calcium, phosphate, bicarbonate, and albumin levels) KFREs, which provide 1-, 2-, and 5-year estimates of the risk of progression to ESRD. 29255845 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 AlteredExpression disease BEFREE Thirty-one children with ESRD and 18 healthy age- and sex-adjusted controls underwent measurement of serum levels of MMP-2, MMP-9, soluble E-selectin, phosphorus, calcium, parathyroid hormone, lipid profile, thrombotic factors, and albumin. 29891747 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE In multivariate analysis, the likelihood of CVC use was lower with increasing dialysis vintage, OR 0.40 (0.26-0.60) for 4 years vs 1 year vintage, rising serum albumin, OR 0.73 (0.59-0.90) per 5 g/L), and with cystic disease as a cause of ESKD, OR 0.38 (95% CI 0.21-0.6). 29609535 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Baseline serum albumin concentration was the predictor variable, and hazard ratios (HRs) for incident ESRD (from US Renal Data System linkage) were calculated in sequentially adjusted models. 29281114 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE When analyzing S-Alb to predict mortality risk in ESRD, it should always be combined with measurement of hsCRP. 29926516 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Low serum albumin level is an independent risk factor for ESRD in patients with IgAN. 29795559 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Micro- and macroalbuminuria were defined as an albumin excretion rate of 20-199 and ≥200 μg/min, respectively, and end-stage renal disease (ESRD) was defined as dialysis or kidney transplantation. 28931542 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE D:A:D participants without SNAEs were followed from first routine sAlb value to the first of a new SNAE [cardiovascular disease (CVD), end-stage liver disease (ESLD), end-stage renal disease (ESRD), non-AIDS malignancy (NADM), death from non-AIDS cause], AIDS-death, 6 months after last visit or 1 February 2016. 29847331 2018
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Surprisingly, patients that reached end stage renal failure (ESRF) had a less severe nephrosis compared to those that did not develop ESRF; serum albumin 33 g/L (3.3 g/dL) versus 24 g/L (2.4 g/dL), p = 0.002 and urinary protein creatinine ratio (uPCR) 550 mg/mmol (5500 mg/g) versus 902 mg/mmol (9020 mg/g), p = 0.0124. 28637442 2017
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE In patients with end-stage renal disease (ESRD), phenytoin-albumin binding is altered and, thus, affects interpretation of total serum levels. 28470115 2017
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 Biomarker disease BEFREE Thus, lower eGFR and higher urinary albumin values are not only predictors of progressive kidney failure, but also of all-cause and CV mortality, independent of each other and of traditional CV risk factors.Although subjects with ESRD are at the highest risk of CV diseases, there will likely be more events in subjects with mil-to-moderate renal dysfunction, because of its much higher prevalence.These findings are even more noteworthy when one considers that a mild reduction in renal function is very common in hypertensive patients.The current European Society of Hypertension (ESH)/European Society of Cardiology (ESC) guidelines for the management of arterial hypertension recommend to sought in every patient signs of subclinical (or asymptomatic) renal damage. 27873229 2017
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.400 GeneticVariation disease BEFREE In the Atherosclerosis Risk in Communities Study (n = 13,277 from 4 US communities), we used structural equation modeling to estimate the association between serum 1,5-AG levels and end-stage renal disease (ESRD) from baseline (1990-1992) through 2013 with adjustment for demographics, risk factors, a latent variable for glycemia (diabetes status, fasting glucose, glycated hemoglobin (HbA1c), fructosamine, glycated albumin), and a latent variable for kidney function (creatinine, cystatin C, β2-microglobulin). 28535187 2017