|
Arteriovenous fistula
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Preoperative serum albumin level and prothrombin time could be the possible risk factors associated with unsuccessful AVF use.
|
31449952 |
2020 |
|
Hyperlipidemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Nucleotide and adenosine conversion rates also correlated with CAVD risk factors, including hyperlipidemia (AMP hydrolysis vs. serum LDL cholesterol: r = - 0.28, p = 0.05; adenosine deamination vs. total cholesterol: r = 0.25, p = 0.05; LDL cholesterol: r = 0.28, p < 0.05; triglycerides: r = 0.32, p < 0.05), hypertension (adenosine deamination vs. systolic blood pressure: r = 0.28, p < 0.05) and thrombosis (ATP hydrolysis vs. prothrombin time: r = - 0.35, p < 0.01).
|
31144065 |
2020 |
|
Acute monocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lower serum creatinine (P = 0.003), higher prothrombin concentration (P = 0.04), lower hematoma size (P = 0.02), and non-AML lesions (P = 0.03) were independent predictors of conservative management success.
|
31686280 |
2020 |
|
Leukemia, Myelocytic, Acute
|
0.010 |
Biomarker
|
disease |
BEFREE |
Lower serum creatinine (P = 0.003), higher prothrombin concentration (P = 0.04), lower hematoma size (P = 0.02), and non-AML lesions (P = 0.03) were independent predictors of conservative management success.
|
31686280 |
2020 |
|
Purpura, Thrombotic Thrombocytopenic
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this case report, we present two SLE patients with thrombocytopenia emergencies secondary to HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome and thrombotic thrombocytopenic purpura (TTP).<b>Areas covered</b>: The first case involved a 26-year-old woman, G1P0 at 26 weeks gestation (GA), with high-titre antiphospholipid antibodies (aPL) (positive lupus anticoagulant, anti-beta 2 glycoprotein-1 (aβ2GP1), anti-cardiolipin) and non-criteria aPL to phosphatidylserine/prothrombin complex and anti-domain 1 β2GP1.
|
31791152 |
2020 |
|
Acute coagulopathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Rats subjected to polytrauma and hemorrhage develop a coagulopathy that is similar to acute coagulopathy of trauma in humans, and is associated with a rise in prothrombin time and a fall in clot strength.
|
31090681 |
2020 |
|
Hyperfibrinolysis
|
0.010 |
Biomarker
|
disease |
BEFREE |
There was an increase in injury severity, prothrombin time ratio, fibrin degradation products and transfusion requirements from the physiological to the shutdown and hyperfibrinolysis phenotypes.
|
31567468 |
2020 |
|
Cardiac Arrhythmia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
After multivariate logistic regression, age, perioperative estimated glomerular filtration rate (eGFR), lactate dehydrogenase (LDH), prothrombin time (PT), with a history of surgery, transfusion, cardiac arrhythmia, coronary heart disease (CHD), or chronic kidney disease (CKD), using calcium channel blocker (CCB), proton pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAID), antibiotic or statin before surgery were predictive factors of CSA-AKI.
|
31243735 |
2019 |
|
beta Thalassemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The β-thalassemia/HbE patients showed significantly higher levels of CD62P and prothrombin fragment 1 + 2 than normal subjects.
|
30988349 |
2019 |
|
Biliary Atresia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Surgical success, the prothrombin time (INR) at presentation, and liver pathology are independent prognostic factors affecting the long-term outcomes in patients with BA.
|
31061002 |
2019 |
|
Colonic Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
This study aimed to analyze prothrombin 3'end gene variants in colon tumor and adjacent normal tissue samples.
|
31704834 |
2019 |
|
Colorectal Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Prothrombin 3' end gene variants may play a role in colorectal cancer.
|
31704834 |
2019 |
|
Dehydration
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We report the case of an 83-year-old man, admitted to our hospital for gastroenteritis, complicated by dehydration and severe prothrombin time prolongation due to oral anticoagulant therapy accumulation, who developed hospital-acquired pneumonia; neither of these illnesses responded to several lines of antibiotic therapy.
|
30626344 |
2019 |
|
Diabetic Retinopathy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Presence of diabetic kidney disease and diabetic peripheral neuropathy, duration of diabetes mellitus, apolipoprotein B, blood urea nitrogen, and prothrombin time were found to be risk factors for DR.
|
31371129 |
2019 |
|
Fibromyalgia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Elevated platelet and RBC counts, PDW values, and fibrinogen levels as well as decreased prothrombin time are all indicative of a prothrombotic state in FM patients, which may be enhanced by an increased inflammatory tone.
|
30654628 |
2019 |
|
Glioblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the present study, hemoglobin, white blood cell, monocyte, neutrophil, leukocyte, and platelet counts, neutrophil/lymphocyte ratio, C-reactive protein, erythrocyte sedimentation rate, activated partial thromboplastin time, prothrombin time, and lactate dehydrogenase levels did not independently predict for overall survival in patients with glioblastoma.
|
30880204 |
2019 |
|
Hematological Disease
|
0.010 |
Biomarker
|
group |
BEFREE |
Conventional coagulation assays (CCAs), prothrombin time (PT)/international normalized ratio (INR) and activated partial thromboplastin time (aPTT), detect clotting factor (CF) deficiencies in hematologic disorders.
|
31136528 |
2019 |
|
Hepatosplenomegaly
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
It is a syndrome of unclear pathophysiology characterized by a reversible anicteric elevation of liver enzymes, alkaline phosphatase, erythrocyte sedimentation rate (ESR), thrombocytosis, prolongation of prothrombin time, and hepatosplenomegaly in the absence of direct hepatobiliary obstruction or jaundice.
|
31824799 |
2019 |
|
Hyperglycemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Clinical characteristics and hematological parameters were compared, including the inflammatory markers (like neutrophil lymphocyte ratio (NLR), monocyte lymphocyte ratio (MLR), and platelet lymphocyte ratio (PLR)) and metabolic features (including hypertension, triglyceridemia, dyslipidemia, and hyperglycemia), as well as hemostatic indices (including prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen).
|
31360265 |
2019 |
|
Hypersplenism
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Diversion surgery in EHPVO, especially mesoportal shunt of Rex, improves hepatic function (prothrombin activity), reduces hypersplenism (platelets, leukocytes, and spleen size), and decreases gastrointestinal bleeding episodes.
|
30086576 |
2019 |
|
Hyperthyroidism
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Haematology, biochemistry, T4, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen and TEG were assessed in control cats and hyperthyroid cats before and 7 and 14 days after RIT.
|
30571457 |
2019 |
|
Liver neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Effects of microbubble-enhanced ultrasound combined with prothrombin on microwave ablation in rabbit VX2 liver tumor.
|
31632546 |
2019 |
|
Multiple Myeloma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The parameters independently associated with the in-hospital death in the EC were Glasgow score, oxygen requirement, fluid overload, blood diastolic pressure, multiple myeloma and prothrombin time.
|
31752723 |
2019 |
|
Nausea
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The overall case-fatality rate was 22.2%; fatal outcome was significantly associated with a negative IgM test result, longer prothrombin time, and nausea.
|
31216260 |
2019 |
|
Pneumonia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Von Willebrand factor-binding protein (vWbp), secreted by <i>Staphylococcus aureus</i> (<i>S. aureus</i>), can activate host prothrombin, convert fibrinogen to fibrin clots, induce blood clotting, and contribute to pathophysiology of <i>S. aureus</i>-related diseases, including infective endocarditis, staphylococcal sepsis and pneumonia.
|
30728809 |
2019 |