Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adipocyte fatty acid-binding protein (FABP4) played critical roles in metabolic syndrome, inflammatory responses and cardiovascular diseases.
|
30969942 |
2019 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
Fatty acid-binding protein-4 (FABP4) is an adipokine associated with obesity and signs of the metabolic syndrome.
|
31025416 |
2019 |
Metabolic Syndrome X
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Circulating FABP4 levels are associated with several aspects of metabolic syndrome and cardiovascular disease.
|
30726793 |
2019 |
Metabolic Syndrome X
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In this study, we demonstrate the specific overexpression of FABP4 in human HCC samples from patients with MS compared to other risk factors for chronic liver disease with FABP4 expression restricted to peritumoral endothelial cells.
|
30575815 |
2019 |
Metabolic Syndrome X
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CTBP1 and MeS modulated the expression of multiple genes (ITGB4, ITGB6, PRSS2, COL17A1 and FABP4) and miRNAs (miR-378a-3p, miR-146a-5p, let-7e-3p, miR-381-5p, miR-194-5p, miR-494-3p) involved in BrCa progression of MDA-MB-231-derived xenografts.
|
29568399 |
2018 |
Metabolic Syndrome X
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Higher plasma AFABP levels are associated with increased risk of metabolic syndrome and cardiovascular morbidity in adults.
|
28324040 |
2017 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
High serum adipocyte fatty acid binding protein level as a potential biomarker of aortic arterial stiffness in hypertensive patients with metabolic syndrome.
|
28860092 |
2017 |
Metabolic Syndrome X
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
After adjustment for age, sex, change in percent body fat and baseline values for other metabolic and inflammatory parameters, FABP4 levels at baseline were shown to be strongly associated with the development of MetS by year 4 (odds ratio (OR), 5.75; 95% confidence interval (CI), 2.71-12.23 for highest tertile vs. lowest tertile, P<0.001)
|
21186114 |
2012 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
All three biomarkers exhibited sexual dimorphisms (levels higher in women for fetuin-A and FABP4 but greater in men for RBP4) and were associated positively with insulin resistance assessed using the homeostasis model, with high-sensitivity C-reactive protein, and with prevalent MetSyn (P<0.01 for all).
|
22855337 |
2012 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results indicate that serum FABP4 is associated with inflammatory factors related to obesity and MS in non-diabetic morbidly obese women.
|
21257725 |
2011 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
Role of adiponectin and adipocyte fatty acid binding protein in the metabolic syndrome.
|
17481768 |
2007 |
Metabolic Syndrome X
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adipose tissue FABP (FABP4) has been suggested to be a bridge between inflammation and other pathways related to the metabolic syndrome.
|
17425064 |
2007 |