Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 AlteredExpression disease BEFREE High expression of ACSL4 predicted a worse prognosis in colorectal cancer, but predicted better prognosis in breast, brain and lung cancer. 27171439 2016
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 AlteredExpression disease BEFREE Here, we focus on functional differences and individual contribution of acyl coA synthetases (ACSL) isoforms to the previously described ACSL/stearoyl-CoA desaturase (ACSL1/ACSL4/SCD) metabolic network causing invasion and poor prognosis in colorectal cancer (CRC). 28894242 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 AlteredExpression disease BEFREE Despite ACSL4 expression is upregulated progressively in CRC-like organoids, metformin is able to downregulate its expression, especially in the first two stages (I, II). 31339921 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.330 GeneticVariation disease UNIPROT