Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 Biomarker disease LHGDN FACL4 is involved in the HCC tumorigenesis and both cAMP and p38 MAPK pathways are associated with the regulation of FACL4 in HCC. 15849811 2005
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 Biomarker disease BEFREE The acyl-CoA synthetase 4 (ACSL4) is increased in breast cancer, colon and hepatocellular carcinoma. 21085606 2010
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 Biomarker disease BEFREE FACL4 is involved in the HCC tumorigenesis and both cAMP and p38 MAPK pathways are associated with the regulation of FACL4 in HCC. 15849811 2005
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 Biomarker disease CTD_human Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression. 19363144 2009
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 AlteredExpression disease BEFREE We found that 14 out of 37 (37.8%) HCC expressed moderate to strong FACL4 immunostaining. 12824887 2003
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 AlteredExpression disease LHGDN We found that 14 out of 37 (37.8%) HCC expressed moderate to strong FACL4 immunostaining. 12824887 2003
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 AlteredExpression disease BEFREE Interestingly, we showed that the expression levels of acyl-CoA synthetase long-chain family member 4 (ACSL4) were negatively associated with those of miR-205 in clinical HCC tissues. 24576478 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 AlteredExpression disease BEFREE In this study, we detected the expression of FACL4 mRNA in 40 patients with hepatic carcinoma and its adjacent normal tissues by semi-quantitative RT-PCR. 18059177 2008
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.360 AlteredExpression disease BEFREE Then, immunohistochemical results demonstrated that the ACSL4 positive expression rate was 70.7% in HCC tissues. 28887439 2017