FGF2, fibroblast growth factor 2, 2247

N. diseases: 635; N. variants: 7
Disease: Brain Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751955
Disease: Brain Infarction
Brain Infarction 		0.310 AlteredExpression disease BEFREE We found that the unfolded protein response (UPR) was strongly activated after HI injury and that bFGF significantly reduced the levels of the ER stress signalling proteins GRP78 and PDI. bFGF also decreased brain infarction volumes and conferred long-term neuroprotective effects against brain atrophy and neuron loss after HI brain injury. 28337259 2017
CUI: C0751955
Disease: Brain Infarction
Brain Infarction 		0.310 Therapeutic disease CTD_human Basic fibroblast growth factor: lysine 134 is essential for its neuroprotective activity. 17524524 2007