FGF3, fibroblast growth factor 3, 2248

N. diseases: 200; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease CTD_human Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. 25822088 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 GeneticVariation disease BEFREE A comparative genomic hybridization analysis using one frozen HCC sample from a responder demonstrated that the 11q13 region, a rare amplicon in HCC including the loci for FGF3 and FGF4, was highly amplified. 22890726 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 AlteredExpression disease BEFREE TMA study showed that overexpression of FGF3 was significantly associated with HCC metastasis and recurrence (p<0.01), suggesting that up-regulation of FGF3 may play an important role in HCC metastasis and recurrence. 17215076 2007
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease BEFREE The cyclin D1 gene was amplified 3-16 fold in five HCCs (11%); among these, the INT-2 gene was also amplified 2-10 fold in four HCCs. 8205525 1994