FGFR3, fibroblast growth factor receptor 3, 2261

N. diseases: 654; N. variants: 55
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker disease BEFREE In this report, we aimed to explore the roles of gene polymorphisms affecting x-ray repair cross complementing 1 (XRCC1), the tumor protein p53 (TP53), and fibroblast growth factor receptor 3 (FGFR3) in the context of susceptibility to cervical cancer. 30616520 2019
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker disease BEFREE The frequency of FGFR3-TACC3-fusion-positive cervical cancer is also 1.9% (2/103) in an independent cohort. 29358619 2018
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker disease BEFREE The research conducted in this article examines a frequently identified fusion protein between FGFR3 and transforming acidic coiled-coil containing protein 3 (TACC3), frequently identified in glioblastoma, lung cancer, bladder cancer, oral cancer, head and neck squamous cell carcinoma, gallbladder cancer, and cervical cancer. 26869289 2016
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker disease BEFREE Fibroblast growth factor receptor-3 (FGFR3) is a receptor tyrosine kinase implicated in the tumorigenesis of multiple malignancies, including bladder and other urothelial cancers, multiple myeloma, and cervical cancer. 22285006 2013
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 GeneticVariation disease UNIPROT Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. 10471491 1999
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.540 Biomarker disease CTD_human