FGFR3, fibroblast growth factor receptor 3, 2261

N. diseases: 654; N. variants: 55
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 AlteredExpression disease BEFREE In agreement with our <i>in vitro</i> and <i>in vivo</i> findings, a high <i>FGFR3-S/FGFR3-L</i> expression ratio in prostate cancer specimens was associated with poor patient prognosis. 31266816 2019
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 Biomarker disease BEFREE In addition, the present study provided the first evidence that the mechanism of action of miRNA‑99a may proceed by directly targeting fibroblast growth factor receptor 3 in prostate cancer. 25352177 2015
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 GeneticVariation disease BEFREE The prevalence of FGFR3 mutations in patients with only PCa was 0%. 20957671 2011
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 AlteredExpression disease BEFREE Mutational activation of FGFR3 is not involved in the development of prostate cancer. 21116115 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 Biomarker disease BEFREE The role of FGFR3 and its abnormalities in prostate cancer are not known. 19377444 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.060 AlteredExpression disease BEFREE FGFR-1 is expressed exclusively as the IIIc isoform in prostate cancer while FGFR-3 is expressed predominantly as the IIIb isoform, similar to the expression pattern in normal prostatic epithelial cells. 11170144 2001