FGFR2, fibroblast growth factor receptor 2, 2263

N. diseases: 731; N. variants: 141
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 GeneticVariation group BEFREE Testing for FGFR2 amplification might be warranted when searching for actionable genomic alterations in sebaceous carcinomas in the mediastinum and in other locations. 31401665 2020
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 AlteredExpression group BEFREE Meanwhile, complex carcinomas presented the highest levels of expression of ESR1, BRCA1 and FGFR2 among all samples. 28945747 2017
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 Biomarker group BEFREE FFPE biopsy tissues are an adequate source for FGFR2 evaluation in gastric carcinomas, and a qPCR-based copy number assay can be used for screening. 25972329 2015
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 Biomarker group BEFREE For that reason, inhibition of FGFR2 could be a therapeutic target in the treatment of endometriod carcinomas. 24448819 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 Biomarker group BEFREE Additionally, we showed that T47D cells stably transfected with constitutively active FGFR-2 gave rise to invasive carcinomas when transplanted into NOD/SCID mice. 21464042 2011
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.060 Biomarker group BEFREE Altogether, these results show that FGFR2-IIIb has tumour growth suppressive properties in bladder carcinomas and suggest possible mechanisms of FGFR2 gene inactivation. 10602477 1999