|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Friend leukemia integration 1 (Fli-1) is a member of the E26 transformation-specific (ETS) transcription factor family.
|
31626853 |
2020 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interestingly, silencing of CD226 in megakaryocytic cells down-regulated the expression of early stage transcription factors includes GATA-binding factor 1 (GATA-1) and friend leukemia integration 1 (FLI-1), but not late-stage nuclear factor, erythroid 2 (NF-E2).
|
30738249 |
2019 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Friend leukemia integration site 1 (FLI-1) nuclear transcription factor has been proposed as a suitable tool in the differential diagnosis of small round cell sarcomas.
|
28605142 |
2017 |
|
Friend leukemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The hematopoietic TFs implicated in patients with impaired platelet function and number include runt-related transcription factor 1, Fli-1 proto-oncogene, E-twenty-six (ETS) transcription factor (friend leukemia integration 1), GATA-binding protein 1, growth factor independent 1B transcriptional repressor, ETS variant 6, ecotropic viral integration site 1, and homeobox A11.
|
28416505 |
2017 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The friend leukemia insertion site 1 (Fli-1) belongs to the Ets family of transcription factors.
|
26424096 |
2016 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
SENCR, a vascular-enriched long noncoding RNA, overlaps the Friend Leukemia Integration virus 1 (FLI1) gene, a regulator of endothelial development.
|
26898221 |
2016 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Friend leukemia virus-induced erythroleukemia-1 (Fli-1), an E26 transformation specific (ETS) transcription factor, was isolated a quarter century ago through a retrovirus mutagenesis screen.
|
24909161 |
2015 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
E26 transformation-specific 1 (ETS1) and friend leukemia integration 1 (FLI1) are members of the ETS family of transcription factors, of which there are 28 in humans.
|
26093983 |
2015 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ewing sarcomas (ES) harbor a chromosomal translocation that fuses the EWS gene to an ETS transcription factor, most commonly Friend leukemia integration 1 (FLI1).
|
23966622 |
2013 |
|
Friend leukemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The expression of friend leukemia integration factor 1 (Fli1), a transcriptional repressor of collagen, was increased after treatment with ciprofloxacin only in SSc fibroblasts, and this was accompanied by a decrease in the levels of DNA methyltransferase 1 (Dnmt1).
|
23041765 |
2012 |
|
Friend leukemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
A growing body of evidence suggests that deficiency of the transcription factor Fli1 (Friend leukemia integration-1) has a pivotal role in the pathogenesis of SSc.
|
20663647 |
2010 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Friend leukemia integration factor 1 (Fli1), an important regulator of immune function and collagen fibrillogenesis, is expressed at reduced levels in endothelial cells in affected skin of patients with SSc.
|
20228226 |
2010 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Friend leukemia integration-1 (Fli-1), a member of the Ets gene family of transcription factors, has been demonstrated to be a target of a leukaemia inducing virus in mice, and is known to be part of a fusion gene in Ewings' sarcoma in humans.
|
16930139 |
2006 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, PU.1 and FLI-1 are dysregulated by Friend leukemia virus insertion in mice resulting in erythroleukemia.
|
8086619 |
1994 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the multistage erythroleukemias induced by the various strains of Friend leukemia virus, the analysis of proviral-integration events has led to the identification of two genes, Fli-1 and Spi-1, both novel members of the ets oncogene family of transcription factors.
|
1406633 |
1992 |
|
Friend leukemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Three ets family members, v-ets, spleen focus forming virus proviral integration 1/Pu.1, and Friend leukemia integration 1 (Fli-1), were shown to be involved in retroviral mediated acute leukemias suggesting that ets family members play a crucial role in transformation.
|
1394211 |
1992 |