Neurodegenerative Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
In summary, our findings indicate that virus-derived peptides targeted to MAST2-PDZ stimulate neurite outgrowth in several neuron types, opening up promising avenues for potentially using NVs in the management of neurodegenerative diseases.
|
31346033 |
2019 |
Stage 0 Breast Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
ACVR2A-rs2382112 (OR<sub>hom</sub> = 3.05, 95%CI = 1.72-5.44, P<sub>hom</sub> = 1.47 × 10<sup>-4</sup> ), MAST2-rs12124649 (OR<sub>hom</sub> = 1.73, 95% CI =1.18-2.54, P<sub>hom</sub> = 5.24 × 10<sup>-3</sup> ), and INSR-rs10500204 (OR<sub>hom</sub> = 1.96, 95% CI = 1.44-2.67, P<sub>hom</sub> =1.68 × 10<sup>-5</sup> ) were associated with increased risk of BCIS; however, only the latter association was significant after correcting for multiple testing.
|
29114882 |
2018 |
Stage 0 Breast Cancer AJCC v6 and v7
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
ACVR2A-rs2382112 (OR<sub>hom</sub> = 3.05, 95%CI = 1.72-5.44, P<sub>hom</sub> = 1.47 × 10<sup>-4</sup> ), MAST2-rs12124649 (OR<sub>hom</sub> = 1.73, 95% CI =1.18-2.54, P<sub>hom</sub> = 5.24 × 10<sup>-3</sup> ), and INSR-rs10500204 (OR<sub>hom</sub> = 1.96, 95% CI = 1.44-2.67, P<sub>hom</sub> =1.68 × 10<sup>-5</sup> ) were associated with increased risk of BCIS; however, only the latter association was significant after correcting for multiple testing.
|
29114882 |
2018 |
Encephalomyelitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Upregulation of Cul9, Mast2, and C4b expression is significantly higher in HFD-EAE mice than ND-EAE mice.
|
27956064 |
2017 |
Azoospermia, Nonobstructive
|
0.010 |
Biomarker
|
disease |
BEFREE |
A Screen for Genomic Disorders of Infertility Identifies MAST2 Duplications Associated with Nonobstructive Azoospermia in Humans.
|
26203179 |
2015 |
Glioblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression.
|
23717670 |
2013 |
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression.
|
23717670 |
2013 |
Adult Glioblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression.
|
23717670 |
2013 |
Childhood Glioblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression.
|
23717670 |
2013 |
Invasive Carcinoma
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Translocations were identified in 16 cases of invasive carcinoma; 10 with MAST2 translocations (2.0%) and 6 cases with NOTCH1 translocations (1.2%).
|
24140425 |
2013 |
Glioblastoma Multiforme
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Using a subcutaneous xenograft mouse model, we also demonstrated that glioblastoma tumor growth requires MAST2 expression.
|
23717670 |
2013 |
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Red Blood Cell Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
Red Blood Cell Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Neutrophil count (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Blood basophil count (lab test)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Reticulocyte count (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Granulocyte count
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
26426971 |
2015 |
Breast Carcinoma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
Breast Carcinoma
|
0.110 |
Biomarker
|
disease |
BEFREE |
MAST2 and NOTCH1 translocations in breast carcinoma and associated pre-invasive lesions.
|
24140425 |
2013 |
Mucinous carcinoma of breast
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Ovarian Mucinous Adenocarcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|