Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
This study shows the benefits of pallidal DBS for the dystonia of PKAN patients.
|
15852393 |
2005 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
DBS effects on dystonia severity were variable but overall marginally effective, with a mean improvement of 7.9% (p = 0.39) at 1-year follow-up and 16.7% (p = 0.46) at last follow-up (mean 47.3 ± 19.9 months after surgery).
|
27743838 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Pallidal deep-brain stimulation of the internal globus pallidus (GPi-DBS) is an effective treatment for dystonia.
|
30623266 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
We aimed to assess whether the thalamic ventral intermediate nucleus (Vim) might be an alternative DBS target in dystonia-choreoathetosis.
|
30718219 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Clinically, no generalization of dystonia was observed after onset and DBS lead to an excellent motor outcome in two cases.
|
26725140 |
2016 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Interestingly, DBS for PD can cause dystonia such as blepharospasm and bilateral pallidal DBS for dystonia can result in features of parkinsonism.
|
31078682 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Pallidal DBS for dystonia in the age of personalized medicine.
|
28964627 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
GPi DBS is an effective and safe treatment in most patients with dystonia.
|
28972096 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
The present study confirms the effectiveness of pallidal DBS in a new family with hereditary primary segmental and generalized dystonia.
|
19890997 |
2009 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
As the course of disease duration as well as the age at operation seem to correlate with DBS outcome in patients with dystonia, DBS at an early stage of development might be beneficial for some of these patients.
|
27289260 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
DBS has been trialed to treat related movement disorders, particularly dystonia.
|
30633810 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Peak low frequency IMC functioned as biomarker for GPi-DBS efficacy, and partly correlated with dystonia severity.
|
31207566 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
A dramatic and long-lasting response to DBS is characteristic of DYT-KMT2B dystonia.
|
31216378 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
We here investigated causes of insufficient response to GPi-DBS in isolated dystonia in a cross-sectional study.
|
28690015 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
GPi-DBS should be considered to ameliorate the invalidating dystonia in these patients.
|
27862284 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
We describe lessons learnt from available dystonia studies and discuss/propose ways to measure DBS and other dystonia-related intervention outcomes.
|
27707656 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
To objectively investigate the impact of GPi-DBS on patients with dystonia on speech fluency, intelligibility, and key aspects of hyperkinetic and hypokinetic dysarthria.
|
29576500 |
2019 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
To assess safety and tolerability of square biphasic DBS in dystonia patients.
|
28195407 |
2017 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
There was a significant improvement of dystonia with GPi-DBS (69 % improvement in Burke-Fahn-Marsden score, p < 0.0001).
|
24178706 |
2014 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
All these results support the multilevel impact of effective DBS on the motor networks in dystonia and suggest potential biomarkers of responsiveness to this treatment.
|
30464181 |
2018 |
Dystonia Disorders
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Some of the rarer types of dystonia that have also been treated with DBS are also described.
|
20083014 |
2009 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Fifty-four subjects with dystonia and DBS for more than 5 years were contacted via social media and were offered to complete a quality-of-life survey comparing current-day life and life prior to DBS.
|
30153389 |
2018 |
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
Our results showed that bilateral GPi DBS in craniocervical dystonia is effective and safe.
|
29246604 |
2017 |