Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0497327
Disease: Dementia
Dementia
0.040 Biomarker disease BEFREE However, a subgroup of patients develops dementia rapidly after DBS despite careful patient selection processes. 28582689 2017
CUI: C0497327
Disease: Dementia
Dementia
0.040 GeneticVariation disease BEFREE This study analyzes changes in body mass index (BMI) in 29 subjects from a prospective, single-blind trial of DBS in early stage PD (age 50-75, Hoehn & Yahr stage II off medication, treated with antiparkinsonian medications for ≥6 months but <4 years, and without a history of motor fluctuations, dyskinesias, or dementia). 28676842 2017
CUI: C0497327
Disease: Dementia
Dementia
0.040 Biomarker disease BEFREE In a subgroup of 60 patients two years after DBS, the ON/ON UPDRS score was associated with YoE (p=0.01; t=-2.42) and diagnosis of PD dementia (p=0.05, t=1.95), while age (p=0.08, t=1.75), disease duration (p=0.6t=0.48) and LEDD (p=0.3; t=1.05) showed no significant association to ON/ON UPDRS score. 28991666 2017
CUI: C0497327
Disease: Dementia
Dementia
0.040 Biomarker disease BEFREE A comprehensive knowledge of the white matter anatomy of the mammillothalamic and mammillotegmental tracts is crucial since they have emerged as new DBS targets in the treatment of various disorders including dementia and epilepsy. 29129763 2018