Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.130 Biomarker disease BEFREE MCF2L is involved in neurotrophin mediated regulation of cell motility in the peripheral nervous system, and thus potentially implicated in nociception in OA. 22178404 2012
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.130 Biomarker disease BEFREE MCF2L regulates a nerve growth factor (NGF), and treatment with a humanized monoclonal antibody against NGF is associated with reduction in pain and improvement in function for knee OA patients. 21871595 2011
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.130 GeneticVariation disease GWASCAT A variant in MCF2L is associated with osteoarthritis. 21871595 2011
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.130 GeneticVariation disease GWASDB A variant in MCF2L is associated with osteoarthritis. 21871595 2011
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.130 GeneticVariation disease BEFREE There are no non-synonymous SNPs that correlate with this association signal and we therefore set out to assess whether its effect on OA susceptibility is mediated by alteration of MCF2L expression. 26584642 2015