PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
We have analyzed high-spatial-resolution STN microelectrode electrophysiology recordings of PD patients (n = 303) that underwent DBS surgery.
|
31758821 |
2020 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
Effects of DBS on freezing of gait and other axial signs in PD patients are unclear.
|
31755599 |
2020 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
This is the first study demonstrating influences of STN-DBS on explicit and implicit emotion processing in PD patients.
|
31466414 |
2019 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
To compare the effect of simultaneous deep brain stimulation of the subthalamic nucleus and substantia nigra pars reticulata (STN+SNr-DBS) to conventional subthalamic stimulation (STN-DBS) on sleep quality in Parkinson's disease (PD) patients.
|
30616868 |
2019 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
We report on the feasibility of DBS target localization in the subthalamic nucleus (STN) by long-latency somatosensory evoked potentials (LL-SSEPs) (>40 msec) in Parkinson's disease (PD) patients.
|
29164724 |
2018 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Veterans Affairs Cooperative Study Program 468 study (CSP 468) produced significant findings regarding deep brain stimulation (DBS) target selection for Parkinson's Disease (PD) treatment, yet its impact on clinical practices has not been described.
|
29249683 |
2018 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, adaptive DBS can be applied with different approaches of stimulation parameter modulation, the feasibility of which can be adapted depending on specific PD phenotypes.
|
30357911 |
2018 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
• Combined information helps localise the PPN as a DBS target for PD patients • Scan the PPN at 7 T and measure its coordinates against different ventricular landmarks • Reconstruct the main fibres around the PPN using diffusion spectrum imaging.
|
29532240 |
2018 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
STN DBS on-state showed marked power increase in the gamma band of PD patients in the frontal and parietal relative to the DBS off-state.
|
27818350 |
2017 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we identified dyskinesias reduction and distance between the active electrodes and the third ventricle as determining factors of weight gain after STN-DBS implantation in PD patients.
|
28913772 |
2017 |
PARKINSON DISEASE, LATE-ONSET
|
0.100 |
Biomarker
|
disease |
BEFREE |
Lately, lesioning of the GPI is being proposed to treat refractory status dystonicus or to treat DBS withdrawal syndrome in PD patients.
|
28590521 |
2017 |