FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety.
|
28616095 |
2017 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Fragile x syndrome.
|
22043169 |
2011 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism.
|
20300527 |
2010 |
FRAXA Syndrome
|
0.350 |
PosttranslationalModification
|
disease |
BEFREE |
In individuals with the fragile X syndrome (FRAXA), the methylation boundary is lost; methylation has penetrated into the FMR1 promoter and inactivated the FMR1 gene.
|
19853235 |
2009 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model.
|
18835858 |
2009 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
BEFREE |
In the present behavioral study, long-term effects of deficiency of FMRP were investigated by examining the acquisition, savings and extinction of delay eyeblink conditioning in male individuals with FRAXA.
|
18616611 |
2008 |
FRAXA Syndrome
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
Ovarian dysfunction and FMR1 alleles in a large Italian family with POF and FRAXA disorders: case report.
|
17428316 |
2007 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion.
|
16510718 |
2006 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome.
|
17065172 |
2006 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Fragile X-associated tremor/ataxia syndrome presenting in a woman after chemotherapy.
|
16043816 |
2005 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
CTD_human |
Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses.
|
15028757 |
2004 |
FRAXA Syndrome
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
Fragile X syndrome (FRAXA) is characterized at the molecular level by an expansion of a naturally occurring 5'-(CGG)(n)-3' repeat in the promoter and 5'-untranslated region (5'-UTR) of the fragile X mental retardation (FMR1) gene on human chromosome Xq27.3.
|
10773084 |
2000 |
FRAXA Syndrome
|
0.350 |
Biomarker
|
disease |
BEFREE |
The gene responsible for the FRAXA syndrome, the FMR1 gene, has been cloned. inactivation of the FMR1 gene is associated with amplification of a trinucle-otide CGG repeat sequence and methylation of an adjacent CpG island.
|
8593539 |
1995 |