|
Parkinson Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In summary, our results thus reveal a new role of FMRP in PD and support the examination of FMRP-regulated genes in PD disease progression.
|
31768670 |
2020 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results indicate that there is a potential association between FMR1 intermediate expanded alleles and PD.
|
27696273 |
2017 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
White matter changes in patients with Parkinson's disease carrying small CGG expansion FMR1 alleles: a pilot study.
|
24401315 |
2014 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
New evidence for, and challenges in, linking small CGG repeat expansion FMR1 alleles with Parkinson's disease.
|
23198693 |
2013 |
|
Parkinson Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The Parkinson disease (Unified Parkinson's Disease Rating Scale) motor score and the measures of cognitive decline (Mini-Mental State Examination and/or Addenbrooke's Cognitive Examination Final Revised Version A scores) were significantly correlated with the size of the CGG repeat and the (elevated) levels of antisense FMR1 and Cytochrome C1 mRNAs in blood leukocytes.
|
21270637 |
2011 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
It is debatable whether the size of triplet repeats of the fragile X mental retardation genes FMR1 and FMR2 (found at the FRAXA and FRAXE loci) is associated with Parkinson's disease (PD).
|
21257332 |
2011 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results, however, suggest that fragile X mental retardation 1 gray-zone alleles may be associated with Parkinson's disease in women.
|
21567456 |
2011 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To determine if patients with parkinsonism and fragile X mental retardation 1 (FMR1) gene expansions have a striatal dopamine deficit similar to Parkinson disease (PD) patients.
|
20702130 |
2010 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To screen DNA samples from a large cohort of females with Parkinson disease for an excess of expanded alleles of the FMR1 gene.
|
19204162 |
2009 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Parkinsonism in FMR1 premutation carriers may be indistinguishable from Parkinson disease.
|
18565783 |
2009 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Parkinsonism in FMR1 premutation carriers may be indistinguishable from Parkinson disease.
|
18565783 |
2009 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Broad screening for premutation alleles in Parkinson disease populations is unlikely to be productive in the absence of additional clinical or family history data that suggest involvement of the FMR1 gene.
|
17620491 |
2007 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
To screen DNA samples (male) from an Italian Parkinson disease clinic for an excess of premutation expansions of the FMR1 gene.
|
17620491 |
2007 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
FMR1 alleles in Parkinson's disease: relation to cognitive decline and hallucinations, a longitudinal study.
|
17548778 |
2007 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Expansions within the FMR1 gene are not associated with PD in our study.
|
15390127 |
2005 |
|
Parkinson Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Premutations in the FMR1 gene as a modifying factor in Parkin-associated Parkinson's disease?
|
15929093 |
2005 |