FOLR1, folate receptor alpha, 2348

N. diseases: 174; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.040 AlteredExpression phenotype BEFREE Recently, the folate receptor alpha has emerged as an attractive theranostic target due to its overexpression in multiple solid tumors and its great functional versatility. 31761235 2020
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.040 Biomarker phenotype BEFREE Various anti- FRα immunotherapeutic strategies are thus currently being developed and clinically assessed for the treatment of various solid tumors. 30770191 2019
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.040 Biomarker phenotype BEFREE In this phase 1 dose-escalation study, the authors investigated IMGN853 in patients with FRα-positive solid tumors. 28440955 2017
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm
0.040 AlteredExpression phenotype BEFREE Folate receptor α (FRα) is overexpressed in a variety of solid tumors and has become an attractive target antigen for immunotherapy purposes. 28498413 2017