Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 AlteredExpression group BEFREE We studied the expression of AP-1 members at the mRNA level in 72 primary breast tumors and 37 adjacent non-tumor tissues and evaluated its correlation with clinicopathological parameters including estrogen receptor (ER), progesterone receptor (PR) and HER2/neu status. 24073962 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker group BEFREE Our studies in a cohort of human breast tumors identified PR and AP-1 nuclear interaction as a marker of good prognosis and better OS in patients treated with tamoxifen (Tam), an anti-estrogen receptor therapy. 24345432 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker group BEFREE In addition, Ad-MMP-9, in combination with radiation, decreased levels of the transcription factors nuclear factor-kappaB and activator protein 1, both of which contribute to the radioresistance of breast tumors. 18519796 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 AlteredExpression group BEFREE In an independent series of breast tumor samples (19 nonrelapsing and 14 relapsing), reduced expression of ESR1/ERalpha, IGFBP4, SNCG, BCL2, and FOS was observed in the relapsing group and was associated with a shorter overall survival. 18928543 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 AlteredExpression group LHGDN Bovine dialyzable leukocyte extract modulates AP-1 DNA-binding activity and nuclear transcription factor expression in MCF-7 breast cancer cells. 18368600 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.350 Biomarker group CTD_human ERE-independent ERalpha target genes differentially expressed in human breast tumors. 16298037 2005