Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279671
Disease: Cervical Squamous Cell Carcinoma
Cervical Squamous Cell Carcinoma
0.050 GeneticVariation disease BEFREE <b>Background and Aims:</b> This study was aim to investigate the relationship between the four intron SNPs (rs3087404, rs2029167, rs2029166 and rs7296239) of SMUG1 and the susceptibility of cervical squamous cell carcinoma. 30662544 2019
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.100 Biomarker disease BEFREE <b>Conclusion:</b> Beyond HK2 expression, <sup>18</sup>F-FDG negativity in (mainly pretreated) MM patients seems to be associated with additional causes not yet known. 30389821 2019
CUI: C0393639
Disease: Hashimoto's encephalitis
Hashimoto's encephalitis
0.030 Biomarker disease BEFREE <b>Conclusion:</b> Brain <sup>18</sup>F-FDG PET/CT may play a significant role in the initial evaluation of patients with clinically suspected antibody-mediated autoimmune encephalitis. 28209905 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE <b>Conclusion:</b> In vivo metabolic tumor profiling in patients with PPGL can be achieved by assessing <sup>18</sup>F-FDG pharmacokinetics using dynamic PET/CT scanning. 30413658 2019
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.070 GeneticVariation disease BEFREE <b>Conclusion:</b> Independent-component analysis of <sup>18</sup>F-FDG PET data showed a gradual disruption of functional brain connectivity with progression of cognitive decline in AD. 28280223 2017
CUI: C0234985
Disease: Mental deterioration
Mental deterioration
0.030 GeneticVariation phenotype BEFREE <b>Conclusion:</b> Independent-component analysis of <sup>18</sup>F-FDG PET data showed a gradual disruption of functional brain connectivity with progression of cognitive decline in AD. 28280223 2017
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
0.050 GeneticVariation group BEFREE <b>Conclusion:</b> Performing <sup>18</sup>F-FDG PET for early evaluation of response often results in a change of management in GIST patients harboring the non-<i>KIT</i> exon 11 mutation and should be considered the standard of care in GIST patients treated with neoadjuvant intent. 28970330 2018
CUI: C0238462
Disease: Medullary carcinoma of thyroid
Medullary carcinoma of thyroid
0.050 Biomarker disease BEFREE <b>Conclusion:</b> Pretherapeutic <sup>18</sup>F-FDG PET/CT provides prognostic information in patients with advanced MTC scheduled for treatment with the TKI vandetanib. 29025983 2018
CUI: C0375071
Disease: Malignant neoplasm of vulva
Malignant neoplasm of vulva
0.020 Biomarker disease BEFREE <b>Conclusion:</b> Standard <sup>18</sup>F-FDG PET/CT is an effective preoperative imaging method for the prediction of LN status in VC, allowing the prediction of pathologically negative groins and thus the selection of patients suitable for minimally invasive surgery. 28546331 2017
CUI: C0677055
Disease: CARCINOMA OF VULVA
CARCINOMA OF VULVA
0.020 Biomarker disease BEFREE <b>Conclusion:</b> Standard <sup>18</sup>F-FDG PET/CT is an effective preoperative imaging method for the prediction of LN status in VC, allowing the prediction of pathologically negative groins and thus the selection of patients suitable for minimally invasive surgery. 28546331 2017
CUI: C0585052
Disease: Chronic sciatica
Chronic sciatica
0.010 Biomarker disease BEFREE <b>Conclusion:</b> The feasibility of <sup>18</sup>F-FDG PET/MRI for diagnosing pain generators in chronic sciatica was demonstrated, revealing various possible etiologies. 29097408 2018
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma
0.100 Biomarker disease BEFREE <b>Conclusion:</b> The identification of additional lesions outside the R-FOV (eyes to thighs) using <sup>18</sup>F-FDG PET/CT has no impact in the definition of the clinical stage of disease and minimal impact in the treatment definition of patients with pediatric lymphoma. 30683766 2019
CUI: C0030472
Disease: Paraneoplastic Syndromes
Paraneoplastic Syndromes
0.010 Biomarker group BEFREE <b>Conclusion:</b> This meta-analysis of available studies demonstrates that whole-body <sup>18</sup>F-FDG PET or <sup>18</sup>F-FDG PET/CT has high diagnostic accuracy and moderate to high sensitivity and specificity for detection of underlying malignancy in patients suspected of having a paraneoplastic syndrome. 27980049 2017
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.100 Biomarker disease BEFREE <b>Conclusion:</b> We confirmed that <sup>18</sup>F-FDG PET scanning is a reliable tool for BMI assessment in HL, and BM biopsy is no longer needed for routine staging. 28126883 2017
CUI: C0220597
Disease: Adult Hodgkin Lymphoma
Adult Hodgkin Lymphoma
0.100 Biomarker disease BEFREE <b>Conclusion:</b> We confirmed that <sup>18</sup>F-FDG PET scanning is a reliable tool for BMI assessment in HL, and BM biopsy is no longer needed for routine staging. 28126883 2017
CUI: C0220644
Disease: Childhood Hodgkin Lymphoma
Childhood Hodgkin Lymphoma
0.100 Biomarker disease BEFREE <b>Conclusion:</b> We confirmed that <sup>18</sup>F-FDG PET scanning is a reliable tool for BMI assessment in HL, and BM biopsy is no longer needed for routine staging. 28126883 2017
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.100 Biomarker disease BEFREE <b>Conclusion:</b> We showed that two radiomic features derived from FDG PET were independently associated with LC in patients with NSCLC undergoing SBRT and could be combined in an accurate predictive model. 31732678 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.100 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT after 1 treatment cycle is predictive of outcome to first-line chemotherapy with bevacizumab in patients with advanced nonsquamous NSCLC. 28336778 2017
CUI: C0279628
Disease: Adenocarcinoma Of Esophagus
Adenocarcinoma Of Esophagus
0.050 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET response to induction chemotherapy could be a useful imaging biomarker to identify patients with esophageal adenocarcinoma who could benefit from subsequent esophagectomy after chemoradiotherapy. 28522744 2017
Polycystic Kidney, Autosomal Dominant
0.010 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT is a useful imaging modality for the evaluation of patients with ADPKD and suspected cyst infection. 29653972 2018
CUI: C0010709
Disease: Cyst
Cyst
0.010 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT is a useful imaging modality for the evaluation of patients with ADPKD and suspected cyst infection. 29653972 2018
CUI: C0278579
Disease: Cervix carcinoma recurrent
Cervix carcinoma recurrent
0.020 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT is highly sensitive in the diagnosis of recurrent cervical cancer. 30210633 2018
CUI: C0278487
Disease: Stage III Breast Cancer AJCC v6
Stage III Breast Cancer AJCC v6
0.010 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT revealed previously unsuspected distant metastases in 16% of male patients with pre-PET/CT stage IIB breast cancer and 33% of those with stage III breast cancer. 30237211 2019
CUI: C3146271
Disease: Stage III Breast Cancer AJCC v7
Stage III Breast Cancer AJCC v7
0.010 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT revealed previously unsuspected distant metastases in 16% of male patients with pre-PET/CT stage IIB breast cancer and 33% of those with stage III breast cancer. 30237211 2019
Anatomic Stage III Breast Cancer AJCC v8
0.010 Biomarker disease BEFREE <b>Conclusion:</b><sup>18</sup>F-FDG PET/CT revealed previously unsuspected distant metastases in 16% of male patients with pre-PET/CT stage IIB breast cancer and 33% of those with stage III breast cancer. 30237211 2019