DDX58, DExD/H-box helicase 58, 23586

N. diseases: 144; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011633
Disease: Dermatomyositis
Dermatomyositis
0.040 Biomarker disease BEFREE The RIG-I pathway is involved in peripheral T cell lymphopenia in patients with dermatomyositis. 31142372 2019
CUI: C0011633
Disease: Dermatomyositis
Dermatomyositis
0.040 Biomarker disease BEFREE RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis. 28738907 2017
CUI: C0011633
Disease: Dermatomyositis
Dermatomyositis
0.040 Biomarker disease BEFREE RIG-I-mediated innate immunity, triggered by a viral or damage signal, plays a significant role in the pathogenesis of DM, but not in that of PM or IBM. 24604766 2014
CUI: C0011633
Disease: Dermatomyositis
Dermatomyositis
0.040 Biomarker disease BEFREE The RIG-I-like receptor IFIH1/MDA5 is a dermatomyositis-specific autoantigen identified by the anti-CADM-140 antibody. 20015976 2010