FXN, frataxin, 2395

N. diseases: 220; N. variants: 21
Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.120 Biomarker disease BEFREE In addition, different models of cardiac iron dysmetabolism will be discussed through the examples of heart failure (cardiomyocyte iron deficiency), myocardial infarction (acute changes in cardiac iron turnover), doxorubicin-induced cardiotoxicity (cardiomyocyte iron overload in mitochondria), thalassaemia (cardiomyocyte cytosolic and mitochondrial iron overload) and Friedreich ataxia (asymmetric cytosolic/mitochondrial cardiac iron dysmetabolism). 31162883 2020
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.120 Biomarker disease BEFREE Acetylation was temporally progressive and paralleled evolution of heart failure in the FXN KO model. 28542596 2017
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.120 Biomarker disease HPO