IL27, interleukin 27, 246778

N. diseases: 286; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker group BEFREE These results are promising, because they are relevant to developing a novel IL-27-based strategy that can treat both the tumor and the bone, by using this simple and effective sonodelivery method for treating prostate tumor bone metastases. 24028178 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Therapeutic group CTD_human These results are promising, because they are relevant to developing a novel IL-27-based strategy that can treat both the tumor and the bone, by using this simple and effective sonodelivery method for treating prostate tumor bone metastases. 24028178 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker group BEFREE Overall, our results suggest that IL-27 may be able to modify interactions between prostate tumor and bone microenvironment cells and thus could be used as a multifunctional therapeutic for restoring bone homeostasis while treating metastatic prostate tumors. 23086758 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker group BEFREE Our results suggest that IL-27 can be effective in reducing tumor growth and can help enhance accumulation of effector cells in prostate tumors in vivo. 21801027 2011
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Therapeutic group CTD_human Our results suggest that IL-27 can be effective in reducing tumor growth and can help enhance accumulation of effector cells in prostate tumors in vivo. 21801027 2011