GAD1, glutamate decarboxylase 1, 2571

N. diseases: 245; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Patients with PNES had higher self-reported anxiety and depression levels (GAD-7: p = 0.04, PHQ-9: p < 0.01; BDI-II: p < 0.01) but similar QOL to PWE (p = 0.78). 31759316 2020
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Our study offers preliminary evidence for use of the PSWQ-A and GAD-7 for assessment of anxiety in a sample of low-income, predominantly African American participants. 30810345 2020
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE To assess the levels of depression and anxiety, the PHQ-9 (The Patient Health Questionnaire), GAD-7 (Generalized Anxiety Disorder), SHS (Subjective Happiness Scale), and IPIP Big-5 questionnaires were used. 31117829 2020
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE In a cross-sectional study, 23 patients with IPF were evaluated using Montreal Cognitive Assessment (MoCA), an instrument for detecting mild cognitive impairments and were screened for OSA through overnight cardiorespiratory polygraphy and for anxiety and depression with three specific scale (Generalized Anxiety Disorder 7-item scale: GAD-7; the Patient Health Questionnaire: PHQ-9; Hospital Anxiety and Depression Scale: HADS). 30707735 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Hearing performance was assessed with Freiburg monosyllabic test and Oldenburg inventory (OI); the health-related quality of life was measured with Nijmegen Cochlear Implantation Questionnaire (NCIQ); depressive symptoms with General Depression Scale (ADS-L); stress with Perceived Stress Questionnaire (PSQ) and anxiety with General Anxiety Disorder-7 (GAD-7). 30870379 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Data were collected by using a pre-developed questionnaire, consisting of socio-demographic information, comprehensive lifestyle information, and psychological health information including a nine-item scale, the Patient Health Questionnaire-9 (PHQ-9) for assessing the level of depression, and a 7-item scale, the Generalized Anxiety Disorder-7 (GAD-7) for assessing the level of anxiety. 31226611 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE There were no significant differences between SCP recipients and controls at 6 months postintervention on self-reported cancer and survivorship knowledge, physical functioning, satisfaction with information provision, or self-efficacy or at 12 months on anxiety, cancer-specific distress, depression, or satisfaction with follow-up care. 31653679 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE The 7-item Generalized Anxiety Disorder Scale (GAD-7) and the 9-item Patient Health Questionnaire (PHQ-9) were used to assess the anxiety and depressive symptoms of the mothers of the autistic children. 31393408 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE A total of 34% reported either a prior diagnosis of depression or scored 10 or greater on the PHQ-8, and 31% reported either a prior diagnosis of anxiety or scored 10 or greater on the GAD-7. 30637564 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Emotional processing theory variables did not predict any anxiety outcomes at posttreatment or follow-up with one exception: Initial fear activation predicted less anxiety at follow-up among youth without GAD. 27355694 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Item response theory-based linking methods were used to create crosswalk tables that convert scores on the GAD-7 to the TBI-QOL Anxiety metric and scores on the PHQ-9 to the TBI-QOL Depression metric. 31498233 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Based on ICIQ-OAB scores, patients were dichotomized as having OAB versus LUTS-other, and GAD-7 scores categorized patients as having anxiety. 31302716 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Of the 36 women who started iCBT, 26 completed all three lessons of treatment (76% adherence rate). iCBT produced moderate to large effect size reductions for anxiety on the GAD-7 (Hedges' g = 0.76) and psychological distress on the Kessler-10 (g = 0.88) that were superior to TAU. 30266030 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Primary outcomes were (a) acceptability of the classes and retention rates and (b) changes in anxiety and depressive symptoms using Generalized Anxiety Disorder 7-item (GAD-7) and Patient Health Questionnaire 9-item (PHQ-9) scales. 31053070 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE The PHQ-9 and GAD-7 were determined to be potential screening tools to aid Chinese medical workers in recognizing depression and anxiety in nonpsychiatric departments. 30762438 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Immunostaining in the basolateral amygdala (BLA) for GAD, a marker for GABA, at the end of the behavioral testing showed the late decrease in anxiety behavior was correlated with upregulation of inhibition. 30728770 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Presence and frequency of depressive symptoms and anxiety were assessed by Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder Questionnaire (GAD-7). 30599337 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 AlteredExpression disease BEFREE Self-report questionnaires were administered to assess quality of life (12-item Kansas City Cardiomyopathy Questionnaire quality of life subscale), level of anxiety (7-item Generalized Anxiety Disorder; GAD-7), level of depression (9-item Patient Health Questionnaire; PHQ-9) and device acceptance (Florida Patient Acceptance Survey; FPAS) to 101 consecutive patients presenting to LVAD clinic. 31346241 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE The Generalized Anxiety Disorder Scale (GAD-7) is an instrument for the assessment of anxiety. 30611061 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE There was no correlation between severity of depressive symptoms (as assessed by GDS-30 and BDI) with anxiety and depressive symptoms except for significant correlation between BDI total score and GAD-7 total score (Pearson correlation coefficient-0.319;p = 0.003).Factor analysis of GDS-30 yielded a five factor solution and when the items of other 3 scales were added, the number of factors/symptoms clusters increased to 7. 30054249 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Participants were also screened for depression using the Neurological Disorder Depression Inventory for Epilepsy (NDDI-E) and the Center for Epidemiologic Studies Depression Scale (CES-D) and for anxiety using the Generalized Anxiety Disorder-7 (GAD-7) scale. 31181426 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE The anxiety symptomatology was assessed using the GAD-7 questionnaire (cut-off ≥ 10 points). 31333520 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Among 200 participants (male, 77.3%; female, 22.8%), 54% had PHQ-9 and 52% had GAD-7 scores indicating moderate to severe depression or anxiety without diagnosis of either disorder. 31571840 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 Biomarker disease BEFREE Taken together, these data suggest that the loss of GAD67 from SOM neurons may lead to the development of anxiety-like but not depression-like states mediated by modification of Akt/GSK3β activities. 31275123 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.100 GeneticVariation disease BEFREE Participants with RA completed the Patient Health Questionnaire (PHQ-2, PHQ-9), Patient Reported Outcomes Measurement Information System Depression Short Form-8a (PROMIS Depression) and Anxiety Short Form-8a (PROMIS Anxiety), Hospital Anxiety and Depression Scale anxiety score (HADS-A) and depression score (HADS-D), Overall Anxiety Severity and Impairment Scale (OASIS), Generalized Anxiety Disorder-2 and 7 item scales (GAD-2, GAD-7) and Kessler-6 scale. 31199570 2019