Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Latent autoimmune diabetes mellitus in adult
0.090 Biomarker disease BEFREE Further logistic regression analysis demonstrated that positivity for TSPAN7A (OR 2.87, p = 0.034), disease duration (OR 1.83, p = 0.019) and GAD antibody titre (OR 2.67, p = 0.009) were risk factors for beta cell function in LADA, while BMI (OR 0.34, p = 0.001) was a protective factor. 30594957 2019
Latent autoimmune diabetes mellitus in adult
0.090 Biomarker disease BEFREE The association was stronger in LADA with low GAD antibody (GADA; <median) (OR 4.25; 95% CI 2.76, 6.52) but present also in LADA with high GADA (OR 2.14; 95% CI 1.42, 3.24). 29589073 2018
Latent autoimmune diabetes mellitus in adult
0.090 AlteredExpression disease BEFREE We aimed to improve the genetic characterisation of LADA and hypothesised that type 2 diabetes-associated gene variants also predispose to LADA, and that the associations would be strongest in LADA patients with low levels of GAD autoantibodies (GADA). 24906951 2014
Latent autoimmune diabetes mellitus in adult
0.090 Biomarker disease BEFREE Genotype frequencies, measures of insulin secretion, and metabolic traits within LADA differed according to GAD antibody (GADA) quartiles, but even the highest quartile differed from type 1 diabetes. 20805278 2010
Latent autoimmune diabetes mellitus in adult
0.090 GeneticVariation disease BEFREE Of type 2 diabetes-associated genes, the CC/CT genotypes of rs7961581 (TSPAN8) and the obesity-linked AA/AC genotypes of rs8050136 (FTO) were associated with LADA in general, but mainly in low anti-GAD LADA patients (P = 0.004 and P = 0.004, respectively). 19833889 2010
Latent autoimmune diabetes mellitus in adult
0.090 GeneticVariation disease BEFREE In addition, the percent of CD8(+) T-cells related with GAD-Ab titers in LADA patients (r=0.292, P=0.03). 17005288 2007
Latent autoimmune diabetes mellitus in adult
0.090 AlteredExpression disease BEFREE There is a significant number of patients with latent autoimmune diabetes in adults (LADA) in Japan, and a high level of GAD autoantibodies has a high predictive value for future insulin deficiency in such patients. 15699499 2004
Latent autoimmune diabetes mellitus in adult
0.090 Biomarker disease BEFREE A high titer of GAD autoantibody has the predictive value of future insulin deficiency in patients with LADA. 12397578 2003
Latent autoimmune diabetes mellitus in adult
0.090 Biomarker disease BEFREE The aim of the study was 1) to establish the prevalence of GAD antibodies (GADab) in a population-based study of type 2 diabetes in western Finland, 2) to genetically and phenotypically characterize this subgroup, and 3) to provide a definition for latent autoimmune diabetes in adults (LADA). 9892237 1999