RAD54B, RAD54 homolog B, 25788

N. diseases: 38; N. variants: 4
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE Consistently, RAD54B knockdown suppressed cell proliferation in vitro, as well as delayed tumor growth in vivo. 31545289 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE A signature was established that could evaluate the overall survival for patients with breast cancer based on the risk score calculated from RAD54B expression and the Tumor-Node-Metastasis (TNM) stage [risk score=expRAD54B × 0.236 + TNM stage (I/II=0 or III/IV=1) ×1.025]. 31612045 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 Biomarker group BEFREE The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer. 28295846 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.040 GeneticVariation group BEFREE Collectively, these data identify SOD1 as a novel candidate cancer drug target and suggest that SOD1 inhibition may have broad-spectrum applicability in a variety of tumor types exhibiting RAD54B deficiencies. 24002644 2013