TENM4, teneurin transmembrane protein 4, 26011

N. diseases: 44; N. variants: 52
Disease: Bipolar Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASCAT A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder. 28115744 2018
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease BEFREE A subsequent meta-analysis of Phase I/II and the Psychiatric GWAS Consortium for BD (PGC-BD) identified another novel BD gene, NFIX (P<sub>best</sub>=5.8 × 10<sup>-10</sup>), and supported three regions previously implicated in BD susceptibility: MAD1L1 (P<sub>best</sub>=1.9 × 10<sup>-9</sup>), TRANK1 (P<sub>best</sub>=2.1 × 10<sup>-9</sup>) and ODZ4 (P<sub>best</sub>=3.3 × 10<sup>-9</sup>). 28115744 2018
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASDB Genome-wide association study reveals two new risk loci for bipolar disorder. 24618891 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease BEFREE Genotyping of five genome-wide significant variants identified for BD (in CACNA1C, ANK3, and ODZ4) was performed in 673 BPD cases and 748 controls. 25304227 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASCAT Genome-wide association study reveals two new risk loci for bipolar disorder. 24618891 2014
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASCAT Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. 23453885 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease BEFREE Our data provide support for two regions, at ODZ4 and CACNA1C, with prior evidence for genome-wide significant (GWS) association in PGC-BD meta-analysis. 23070075 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASDB Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. 23070075 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASDB Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. 22182935 2013
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 Biomarker disease BEFREE In addition to pathway enrichment, the collective network approach elevates the importance of ANK3, DGKH and ODZ4 for BD susceptibility in the WTCCC GWAS, despite their weak single-locus effect in the data. 22892719 2012
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASDB An analysis of all 11,974 bipolar disorder cases and 51,792 controls confirmed genome-wide significant evidence of association for CACNA1C and identified a new intronic variant in ODZ4. 21926972 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease GWASCAT An analysis of all 11,974 bipolar disorder cases and 51,792 controls confirmed genome-wide significant evidence of association for CACNA1C and identified a new intronic variant in ODZ4. 21926972 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 Biomarker disease CTD_human An analysis of all 11,974 bipolar disorder cases and 51,792 controls confirmed genome-wide significant evidence of association for CACNA1C and identified a new intronic variant in ODZ4. 21926972 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.450 GeneticVariation disease BEFREE Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011