CNTNAP2, contactin associated protein 2, 26047

N. diseases: 203; N. variants: 46
Disease: Specific language impairment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 Biomarker disease BEFREE Deletions within CNTNAP2 were found in two children with CAS but not in any of the children with SLI. 26097074 2015
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 GeneticVariation disease BEFREE We studied the potential contribution to stuttering from variants in the FOXP2 gene, which have previously been associated with developmental verbal dyspraxia, and from variants in the CNTNAP2 gene, which have been associated with specific language impairment (SLI). 24807205 2014
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 GeneticVariation disease BEFREE We propose that these CNTNAP2 variants increase susceptibility to SLI or autism when they occur together with other risk factors. 21310003 2011
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 GeneticVariation disease BEFREE At a gene level, CAM genes associated in all three samples (NRXN1 and CNTNAP2), which were previously implicated in specific language disorder, autism and schizophrenia. 20157312 2011
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 GeneticVariation disease BEFREE We examined association of a susceptibility gene, contactin-associated protein-like 2 (CNTNAP2), for ASDs and specific language impairment with SM and social anxiety-related traits. 21193173 2011
CUI: C0454651
Disease: Specific language impairment
Specific language impairment 		0.060 GeneticVariation disease BEFREE Disruption of a number of these genes (including NRXN1, CNTNAP2 and CASK) are known to cause diverse neurodevelopmental brain disorder phenotypes including schizophenia, autism, learning disability and specific language disorder. 20574149 2011