TES, testin LIM domain protein, 26136

N. diseases: 67; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 Biomarker disease BEFREE TES suppressed GC cell proliferation and colony formation, induced cell cycle arrest, and inhibited tumorigenicity in vitro. 30728082 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 Biomarker disease BEFREE The efficiency of TES and FLN-C degradation is significantly potentiated by K<sup>139</sup>-acetylated Siah2 (ac-K<sup>139</sup> Siah2) in infected gastric cancer cells (GCCs). ac-Siah2-mediated downregulation of TES and FLN-C disrupts filopodia structures but promotes lamellipodia formation and enhances invasiveness and migration of infected GCCs. 30063986 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 Biomarker disease BEFREE However, only TES showed the potential to be a TSG associated with GC. 20626849 2010
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.040 Biomarker disease BEFREE The results show that CAV1, CAV2, and TESTIN are not tumor suppressor genes in this gastric cancer. 12620387 2003