GATA4, GATA binding protein 4, 2626

N. diseases: 336; N. variants: 72
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.320 Biomarker disease CTD_human Methylation of GATA4/5 is a common and specific event in colorectal carcinomas, and GATA4/5 exhibit tumor suppressive effects in colorectal cancer cells in vitro. 19509152 2009
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.320 Biomarker disease BEFREE Methylation of GATA4/5 is a common and specific event in colorectal carcinomas, and GATA4/5 exhibit tumor suppressive effects in colorectal cancer cells in vitro. 19509152 2009
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.320 PosttranslationalModification disease BEFREE We now show that in colorectal cancer (CRC) and gastric cancer promoter hypermethylation and transcriptional silencing are frequent for GATA-4 and -5 but are never seen for GATA-6. 14612389 2003