Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0011265
Disease: Presenile dementia
Presenile dementia
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset
0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
CUI: C4021107
Disease: Non-obstructive azoospermia
Non-obstructive azoospermia
0.020 Biomarker disease BEFREE Similarly, expressions of BNC1, TAF7L, YBX2, ODF1, and GAPDHS were significantly decreased in the testis of men with non-obstructive azoospermia (NOZ). 31065688 2020
CUI: C4021107
Disease: Non-obstructive azoospermia
Non-obstructive azoospermia
0.020 Biomarker disease BEFREE Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients. 23675907 2013
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.010 Biomarker group BEFREE Based on the literature data on the importance of GAPDS for the motility of sperms in diabetic men, it was concluded that the decrease in the sperm motility and GAPDS activity in the presence of high glucose or diabetes mellitus is due to oxidation of GAPDS and inhibition of glycolysis by the reactive oxygen species produced by sperms. 26255202 2015
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE GAPDS showed greater toxicity against cancer cells compared to a known GAPDH enzyme inhibitor. 25308277 2014
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.010 Biomarker phenotype BEFREE GAPDS also selectively inhibited cell migration and invasion. 25308277 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE GAPDS showed greater toxicity against cancer cells compared to a known GAPDH enzyme inhibitor. 25308277 2014
CUI: C0025202
Disease: melanoma
melanoma
0.010 Biomarker disease BEFREE Immunocytochemical staining of melanoma cells revealed native GAPDS in the cytoplasm. 23026046 2012