GCG, glucagon, 2641

N. diseases: 441; N. variants: 10
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.320 Biomarker disease BEFREE We studied the action of GLP-2 on myofibroblasts from colon cancer and adjacent tissue, and the effects of conditioned medium from these cells on epithelial cell proliferation, migration and invasion. 28363795 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.320 Biomarker disease CTD_human AOM-DSS mice treated with vehicle or hGly(2)GLP-2 had high-grade dysplasia/colon cancer incidences of 56 and 64%, respectively, compared with 46% in hGLP-2(3-33)-treated AOM-DSS animals (P < 0.05). 22323126 2012
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.320 Biomarker disease BEFREE Moreover, chronic GLP-2 administration had no effect on the growth of human colon cancer cell xenografts in nude mice in vivo. 18829546 2008