GCKR, glucokinase regulator, 2646

N. diseases: 136; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.120 Biomarker disease BEFREE This study suggests that increased glucokinase-GKRP disruption has beneficial effects on eGFR, but these may be offset by a disadvantageous effect on coronary artery disease risk. 30352097 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.120 GeneticVariation disease GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.120 GeneticVariation disease BEFREE Our findings confirmed the contribution of GCKR rs780093 polymorphism to TG metabolism and demonstrated GCKR rs780093 as a risk factor of CHD in individuals aged 65 and older. 24385677 2013
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.120 GeneticVariation disease GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011